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Forebrain Development Pathway Bioinformatics

Disease and disorder research has been conducted in relation to the Forebrain Development Pathway and Holoprosencephaly, Nervousness, Congenital Abnormality, Cyclocephaly, Crest Syndrome. The study of the Forebrain Development Pathway has been mentioned in research publications which can be found using our bioinformatics tool below. The Forebrain Development Pathway has been researched in relation to Brain Development, Cell Proliferation, Neurogenesis, Gastrulation, Localization. The Forebrain Development Pathway complements our catalog of research reagents including antibodies and ELISA kits against SHH, FGF8, WNT, BMP4, FOXG1.

Top Research Reagents

We have 1424 products for the study of the Forebrain Development Pathway that can be applied to Chromatin Immunoprecipitation (ChIP), Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

Choline Acetyltransferase/ChAT Antibody
NBP1-30052
Western Blot: Choline Acetyltransferase/ChAT Antibody [NBP1-30052] - The decrease in protein expressions of c-kit, Choline Acetyltransferase/ChAT, nNOS and Cx43 in the colon of elderly humans. Expressions of c-kit, ChAT, nNOS and Cx43 proteins in colonic muscle layers detached from youth and older adults were examined by western blotting (n=4 per group), and similar reduction was observed. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/30530917/) licensed under a CC-BY license.Immunocytochemistry/Immunofluorescence: Choline Acetyltransferase/ChAT Antibody [NBP1-30052] - Representative images of lumbar spinal cord sections at 130 days immunostained with Choline Acetyltransferase/ChAT. Scale bar, 200 um. Image collected and cropped by CiteAb from the following publication (https://embomolmed.embopress.org/lookup/doi/10.15252/emmm.201808888), licensed under a CC-BY license.

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

22 Publications
FOXG1 Antibody
NBP1-56594
Western Blot: FOXG1 Antibody [NBP1-56594] - Jurkat cell lysate, Antibody Titration: 5.0-8.0ug/mlImmunohistochemistry-Paraffin: FOXG1 Antibody [NBP1-56594] - Human Liver Tissue, antibody concentration 4-8ug/ml. Cells with positive label: Hepatocytes (indicated with arrows) 400X magnification.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

1 Publication
SIX3 Antibody (1A2)
H00006496-M04
Western Blot: Six3 Antibody (1A2) [H00006496-M04] - Analysis of SIX3 expression in FHs 173 WE.Western Blot: Six3 Antibody (1A2) [H00006496-M04] - Analysis of SIX3 expression in 293 (Cat # L026V1).

Mouse Monoclonal
Species Human
Applications WB, ELISA

HESX1 Antibody
NBP1-89090
Immunohistochemistry-Paraffin: HESX1 Antibody [NBP1-89090] - Staining of human testis shows moderate to strong nuclear positivity in cells in seminiferous ducts as well as in Leydig cells.Immunohistochemistry-Paraffin: HESX1 Antibody [NBP1-89090] - Staining of human skeletal muscle shows no nuclear positivity in striated muscle fibers as expected.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

ELSPBP1 Antibody
NBP2-13957
Immunohistochemistry-Paraffin: ELSPBP1 Antibody [NBP2-13957] - Analysis in human epididymis and prostate tissues. Corresponding ELSPBP1 RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: ELSPBP1 Antibody [NBP2-13957] - Staining of human cerebral cortex, epididymis, prostate and testis using Anti-ELSPBP1 antibody NBP2-13957 (A) shows similar protein distribution across tissues to independent antibody NBP2-13958 (B).

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

SS18L1 Antibody
NBP2-20486
Western Blot: SS18L1 Antibody [NBP2-20486] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 10% SDS PAGE gel, diluted at 1:1000.Immunocytochemistry/Immunofluorescence: SS18L1 Antibody [NBP2-20486] - Immunofluorescence analysis of paraformaldehyde-fixed A431, using antibody at 1:500 dilution.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

Zic2 Antibody
NBP2-24607
Western Blot: Zic2 Antibody [NBP2-24607] - Analysis of ZIC2 in HepG2 cell lysate using 1) pre-bleed, and 2) this antibody. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

Rabbit Polyclonal
Species Human, Mouse, Bovine
Applications WB

Otx2 Antibody [Unconjugated]
AF1979
Western blot shows lysates of IMR-32 human neuroblastoma cell line. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human Otx2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1979) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=Otx2 was detected in immersion fixed NTera-2 human testicular embryonic carcinoma cell line using Goat Anti-Human Otx2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1979) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (yellow, upper panel; Catalog # <a class=

Goat Polyclonal
Species Human
Applications WB, Simple Western, IHC

     2 Reviews

163 Publications
GLI-3 Antibody
AF3690
Western blot shows lysates of mouse embryo tissue. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human/Mouse GLI-3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3690) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=Jurkat human acute T cell leukemia cell line treated with 50 ng/mL PMA and 200 ng/mL calcium ionomycin for 30 minutes was fixed using formaldehyde, resuspended in lysis buffer, and sonicated to shear chromatin. GLI‑3/DNA complexes were immunoprecipitated using 5 μg Goat Anti-Human/Mouse GLI‑3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3690) or control antibody (Catalog # <A class=NoLineLink href=

Goat Polyclonal
Species Human, Mouse
Applications WB, ChIP, ICC

     3 Reviews

100 Publications
EMX2 Antibody [Unconjugated]
AF6470
Western blot shows lysates of HepG2 human hepatocellular carcinoma cell line and NIH-3T3 mouse embryonic fibroblast cell line. PVDF Membrane was probed with 1 µg/mL of Human EMX2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6470) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (<a class=EMX2 was detected in immersion fixed paraffin-embedded sections of uterus using Sheep Anti-Human/Mouse EMX2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6470) at 1 µg/ml overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using VisUCyte Antigen Retrieval Reagent-Basic (Catalog # <a class=NoLineLink href=

Sheep Polyclonal
Species Human, Mouse
Applications WB, IHC

1 Publication
Pax6 Antibody [Unconjugated]
AF8150
Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line and rat cortical stem cells. PVDF membrane was probed with 0.5 µg/mL of Sheep Anti-Human Pax6 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF8150) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # <a class=Immersion fixed SA01 human embryonic stem cells were differentiated for 6 days with Recombinant Human Noggin (Catalog # <A class=NoLineLink href=

Sheep Polyclonal
Species Human
Applications WB, Simple Western, ICC

15 Publications
Sonic Hedgehog/Shh [Unconjugated]
464-SH
Recombinant Mouse Sonic Hedgehog/Shh (C25Il), N-Terminus (Catalog # 464-SH) induces alkaline phosphatase production by the C3H10T1/2 mouse embryonic fibroblast cell line. The activity is more than 30-fold greater than the top competitor's Sonic Hedgehog.Recombinant Mouse Sonic Hedgehog/Shh (C25II), N-Terminus (Catalog # 464-SH) has a molecular weight (MW) of 20.7 kDa as analyzed by SEC-MALS, suggesting that this protein is a monomer.  MW may differ from predicted MW due to post-translational modifications (PTMs) present (i.e. Glycosylation).


Species Mouse
Applications BA

65 Publications
FGF-8 [Unconjugated]
423-F8
Recombinant Human/Mouse FGF-8b (Catalog # 423-F8) stimulates cell proliferation in the NR6R‑3T3 mouse fibroblast cell line. The ED<sub>50</sub> for this effect is 6.5-40 ng/mL in the presence of 1 μg/mL heparin.1 μg/lane of Recombinant Human/Mouse FGF-8b was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 23 kDa.


Species Human, Mouse
Applications BA

     1 Review

60 Publications
BMP-4 [Unconjugated]
314-BP
Recombinant Human BMP‑4 (Catalog # 314-BP) induces BMP responsive SEAP reporter activity in HEK293 human embryonic kidney cells. The ED<sub>50</sub> for this effect is 0.70-7.00 ng/mL.1 ug/lane of Recombinant Human BMP-4 was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing major bands at 22-25 kDa and 37-41 kDa, respectively. Multiple bands in gel are due to variable glycosylation.<p style=


Species Human
Applications BA, BA

503 Publications
TTF-1 / NKX2-1 Antibody (NX2.1/690) - Azide and BSA Free
NBP2-47772
Immunohistochemistry-Paraffin: TTF-1 / NKX2-1 Antibody (NX2.1/690) - Azide and BSA Free [NBP2-47772] - Human Thyroid stained with TTF-1 Monoclonal Antibody (NX2.1/690)Immunohistochemistry-Paraffin: TTF-1 / NKX2-1 Antibody (NX2.1/690) - Azide and BSA Free [NBP2-47772] - Human Lung Adenocarcinoma stained with TTF-1 Monoclonal Antibody (NX2.1/690)

Mouse Monoclonal
Species Human, Mouse, Rat
Applications Flow, ICC/IF, IHC

GFAP Antibody
NB300-141
Immunohistochemistry: GFAP Antibody [NB300-141] - Analysis of a rat cerebellum section stained with rabbit polyclonal antibody to GFAP, NB300-141, dilution 1:5000 in green and mouse monoclonal antibody to MeCP2, dilution 1:500, in red. The blue is DAPI staining of nuclear DNA. Following transcardial perfusion of rat with 4% paraformaldehyde, brain was post fixed for 1 hour, cut to 45 uM, and free-floating sections were stained with above antibodies. The GFAP antibody stains the network of astrocytic cells and the processes of Bergmann glia in the molecular layer. The MeCP2 antibody specifically labels nuclei of certain neurons.Immunocytochemistry/Immunofluorescence: GFAP Antibody [NB300-141] - Rat neurons stained with Neurofilament Heavy antibody NB300-217 (red) and GFAP antibody NB300-141 (green).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ICC/IF

     12 Reviews

102 Publications
LRP2 Antibody (CD7D5) - Azide and BSA Free
NB110-96417
Immunohistochemistry: LRP2 Antibody (CD7D5) [NB110-96417] - Representative immunofluorescence stainings of control (Tead4m-z+) and Tead4 maternal/zygotic mutant (Tead4m-z-) embryos for Krt8 and Krt18 (16 cell stage embryos) and Lrp2 and Dab2 (32 to 64 cell stage embryos; Lrp2 and Dab2 were not detected in earlier stage embryos). n indicates total number of embryos analyzed. Scale bar: 25 um. Image collected and cropped by CiteAb from the following publication (elifesciences.org/articles/22906), licensed under a CC-BY license.Immunohistochemistry-Paraffin: LRP2 Antibody (CD7D5) [NB110-96417] - Staining (paraffin-embedded tissue-sections fixed in formalin) of Megalin in the brush border of the proximal tubule.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications ICC/IF, IHC, IHC-Fr

     1 Review

18 Publications