Species: Hu, Mu, Rt, Ba, I, Pm, Pp
Applications: WB, ELISA, Func, ICC/IF, IHC, IP, KD
Host: Mouse Monoclonal
Species: Hu, Mu, Ch, Pm, Xp, Ze
Applications: WB, ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, IP, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: AC
Species: Hu
Applications: PAGE
Description
TARDBP, also known as TAR DNA binding protein, is a DNA and RNA-binding protein which regulates transcription and splicing. TARDBP is also involved in the regulation of CFTR splicing and promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. TARD-BP may also be involved in microRNA biogenesis, apoptosis and cell division. TARDBP can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat.
Bioinformatics
| Entrez |
Mouse
Human
|
| Uniprot |
Human
Human
Human
Human
Human
|
| Product By Gene ID |
23435 |
| Alternate Names |
- ALS10TAR DNA-binding protein-43
- TAR DNA binding protein
- TDP43
- TDP-43
- TDP-43TAR DNA-binding protein 43
|
![Western Blot TDP-43/TARDBP Antibody (671834) [Unconjugated]](http://images.novusbio.com/fullsize2/TDP-43_MAB7778_Western_Blot_12741.jpg)
![Western Blot TDP-43/TARDBP Antibody (671834) [Unconjugated]](http://images.novusbio.com/fullsize2/TDP43_MAB7778_Western_Blot_21383.jpg)
![Immunocytochemistry TDP-43/TARDBP Antibody (671834) [Unconjugated]](http://images.novusbio.com/fullsize2/TDP43_MAB7778_Immunocytochemistry__Immunofluorescence_21481.jpg)
![Immunohistochemistry TDP-43/TARDBP Antibody (671834) [Unconjugated]](http://images.novusbio.com/fullsize2/TDP43_MAB7778_Immunohistochemistry_19254.jpg)
![Simple Western TDP-43/TARDBP Antibody (671834) [Unconjugated]](http://images.novusbio.com/fullsize2/TDP43_MAB7778_Simple_Western_21893.jpg)
![Immunoprecipitation TDP-43/TARDBP Antibody (671834) [Unconjugated]](http://images.novusbio.com/fullsize2/mab7778_human-mouse-rat-tdp-43-tardbp-mab-clone-671834-immunoprecipitation-22112022133010.jpg)
