Species: Hu, Mu, Rt, Po, Am, Ca, Gp, Rb, Sh
Applications: WB, Flow, ICC/IF, IHC, IP
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Ch, Po, Ca, Fe, Rb
Applications: WB, ICC/IF, IP, ChIP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Po, Am, Bv, Ca, Gp, Ha, Pm, Rb, Sh, V-Vi
Applications: WB, ELISA, Flow, ICC/IF, IHC, B/N
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Sarcoplasmic/endoplasmic reticulum Calcium-ATPase 2 (SERCA2) is a magnesium-dependent pump that catalyzes the hydrolysis of ATP and translocates calcium from the cytosol to the sarcoplasmic reticulum lumen. There are 2 SERCA2 isoforms that differ in the 3' UTR. The SERCA2A isoform is highly expressed in heart and slow twitch skeletal muscle and is important to the regulation of the contraction and relaxation cycle, while the SERCA2B isoform is expressed in smooth muscle and adult epidermis. SERCA2 is also known as ATP2A2, ATP2B, DAR, DD, and MGC45367.
Bioinformatics
Entrez |
Rabbit Mouse Rat Canine Human |
Uniprot |
Human Human Canine Human |
Product By Gene ID |
488 |
Alternate Names |
- ATP2BFLJ20293
- ATPase, Ca++ dependent, slow-twitch, cardiac muscle-2
- ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
- Calcium pump 2
- Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletalmuscle isoform
- cardiac Ca2+ ATPase
- DAR
- DD
- EC 3.6.3
- EC 3.6.3.8
- Endoplasmic reticulum class 1/2 Ca(2+) ATPase
- FLJ38063
- MGC45367
- sarcoplasmic/endoplasmic reticulum calcium ATPase 2
- SERCA2DKFZp686P0211
- SR Ca(2+)-ATPase 2
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