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Zic2 Antibody

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Western Blot: Zic2 Antibody [NBP2-24607] - Analysis of ZIC2 in HepG2 cell lysate using 1) pre-bleed, and 2) this antibody. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.
Western Blot: Zic2 Antibody [NBP2-24607] - Analysis of ZIC2 in HepG2 cell lysate using 1) pre-bleed, and 2) this antibody. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for ...read more

Product Details

Summary
Reactivity Hu, Mu, Bv, Ca, Ch, Eq, Pm, Rt, PmSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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Zic2 Antibody Summary

Immunogen
A portion of amino acid 350 to 400 of human ZIC2 was used as immunogen.
Predicted Species
Rat (100%), Monkey (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ZIC2
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 4-7 ug/ml

Reactivity Notes

The amino acid sequence used as immunogen is 88% homologous in Xenopus and Chicken.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.2 ml PBS and 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A purified

Alternate Names for Zic2 Antibody

  • HPE5Zic family member 2 (odd-paired Drosophila homolog)
  • Zic family member 2 (odd-paired homolog, Drosophila)
  • Zinc finger protein of the cerebellum 2
  • zinc finger protein ZIC 2

Background

ZIC2 (zinc finger protein of the cerebellum 2) is a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. In mouse, knockout of Zic1 leads to aplasia of cerebellum and skeletal abnormalities. Mutation in Zic2 and Zic3 in mouse and/or human cause holoprosencephaly and heterotaxis, respectively. Holoprosencephaly is the most common structural anomaly of the human brain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ZIC2
Uniprot