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WWOX Antibody [PE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
PE

Order Details

WWOX Antibody [PE] Summary

Immunogen
The immunogen this antibody was made to, maps to a region between residue 364 to 414 of human WW Domain Containing Oxidoreductase using the numbering given in entry P_057457.1 (GeneID 51741).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
WWOX
Purity
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for WWOX Antibody [PE]

  • D16S432E
  • EC 1.1.1
  • EC 1.1.1.-
  • FOR
  • FORHHCMA56
  • FRA16D
  • Fragile site FRA16D oxidoreductase
  • SDR41C1
  • short chain dehydrogenase/reductase family 41C, member 1
  • WOX1
  • WOX1PRO0128
  • WW domain containing oxidoreductase
  • WW domain-containing oxidoreductase
  • WW domain-containing protein WWOX
  • WWOX

Background

WW domain-containing oxidoreductase (WWOX) is a proapoptotic protein and a tumor suppressor gene. Because mutation or deletion in the coding region of WWOX is rarely found, it is speculated that the appearance of aberrant transcripts affects progression of many cancers. In addition, protein levels of WWOX, its Tyr33-phosphorylated form, and WOX2 are significantly down-regulated in the neurons of Alzheimer's hippocampi.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol WWOX