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VLDLR Antibody (VLDLR/1337)

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Immunohistochemistry-Paraffin: VLDLR Antibody (VLDLR/1337) [NBP2-53351] - Formalin-fixed, paraffin-embedded human Pancreas stained with VLDL-Receptor Monoclonal Antibody (VLDLR/1337).

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications IHC
Clone
VLDLR/1337
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.2 mg/ml

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VLDLR Antibody (VLDLR/1337) Summary

Description
200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP2-54553)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.
Immunogen
Recombinant human VLDLR fragment from c-terminal (Uniprot: P98155)
Localization
Cytoplasmic
Isotype
IgG1 Lambda
Clonality
Monoclonal
Host
Mouse
Gene
VLDLR
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0 for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
10 mM PBS with 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.2 mg/ml
Purity
Protein A or G purified

Alternate Names for VLDLR Antibody (VLDLR/1337)

  • CARMQ1
  • CHRMQ1
  • FLJ35024
  • very low density lipoprotein receptor
  • very low-density lipoprotein receptor
  • VLDL R
  • VLDL receptor
  • VLDLR
  • VLDL-R
  • VLDLRCH

Background

VLDL (very low density lipoprotein) cholesterol is one of the three major types of cholesterol found in blood. VLDL receptor plays an essential role in triglyceride metabolism. It binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol VLDLR
Uniprot