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VDR/NR1I1/Vitamin D Receptor Antibody [CoraFluor™ 1]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-98841AF350
Alexa Fluor 405
NBP2-98841AF405
Alexa Fluor 488
NBP2-98841AF488
Alexa Fluor 532
NBP2-98841AF532
Alexa Fluor 594
NBP2-98841AF594
Alexa Fluor 647
NBP2-98841AF647
Alexa Fluor 700
NBP2-98841AF700
Alexa Fluor 750
NBP2-98841AF750
Allophycocyanin
NBP2-98841APC
Biotin
NBP2-98841B
DyLight 350
NBP2-98841UV
DyLight 405
NBP2-98841V
DyLight 488
NBP2-98841G
DyLight 550
NBP2-98841R
DyLight 594
NBP2-98841DL594
DyLight 650
NBP2-98841C
DyLight 680
NBP2-98841FR
DyLight 755
NBP2-98841IR
FITC
NBP2-98841F
HRP
NBP2-98841H
Janelia Fluor 525
NBP2-98841JF525
Janelia Fluor 549
NBP2-98841JF549
Janelia Fluor 646
NBP2-98841JF646
Janelia Fluor 669
NBP2-98841JF669
PE
NBP2-98841PE
PerCP
NBP2-98841PCP
Unconjugated
NBP2-98841-100ul
mFluor Violet 450 SE
NBP2-98841MFV450
mFluor Violet 500 SE
NBP2-98841MFV500
mFluor Violet 610 SE
NBP2-98841MFV610
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VDR/NR1I1/Vitamin D Receptor Antibody [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human VDR/NR1I1/Vitamin D Receptor.
Predicted Species
Mouse (100%), Rat (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
VDR
Purity
Antigen and protein A Affinity-purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Antigen and protein A Affinity-purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for VDR/NR1I1/Vitamin D Receptor Antibody [CoraFluor™ 1]

  • NR1I1
  • NR1I1Nuclear receptor subfamily 1 group I member 11,25-dihydroxyvitamin D3 receptor
  • VDR
  • vitamin D1,25- dihydroxyvitamin D3 receptor
  • vitamin D3 receptor

Background

Vitamin D Receptor encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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VDR/NR1I1/Vitamin
D Receptor Antibody [ ...
NBP2-98841CL1
VDR/NR1I1/Vitamin D Receptor Antibody [CoraFluor™ 1]
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol VDR