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VDAC1 Antibody (C1)

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Immunohistochemistry-Paraffin: VDAC1 Antibody (C1) [NBP3-42163] - DAB staining on IHC-P; Sample: Human Liver Tissue; Primary Ab: 10ug/ml NBP3-42163; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
Immunohistochemistry-Paraffin: VDAC1 Antibody (C1) [NBP3-42163] - DAB staining on IHC-P; Sample: Human Liver Tissue; Primary Ab: 10ug/ml NBP3-42163; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal ...read more
Immunohistochemistry-Paraffin: VDAC1 Antibody (C1) [NBP3-42163] - DAB staining on IHC-P; Sample: Human Cardiac Muscle Tissue; Primary Ab: 10ug/ml NBP3-42163; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG ...read more
Western Blot: VDAC1 Antibody (C1) [NBP3-42163] - Sample: Recombinant VDAC1, Human.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
C1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

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VDAC1 Antibody (C1) Summary

Immunogen
Immunized with recombinant Human VDAC1 (Uniprot#: P21796; Ala2-Ala283 (Uniprot#: P21796)
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
VDAC1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunohistochemistry 5-20ug/mL
  • Western Blot 0.5-2ug/mL

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.01M PBS, pH7.4, 50% glycerol
Preservative
0.05% Proclin 300
Concentration
1 mg/ml
Purity
Protein A or G purified

Alternate Names for VDAC1 Antibody (C1)

  • hVDAC1
  • MGC111064
  • Outer mitochondrial membrane protein porin 1
  • Plasmalemmal porin
  • Porin 31HL
  • Porin 31HM
  • PORIN
  • PORIN-31-HL
  • VDAC
  • VDAC1
  • VDAC-1
  • voltage-dependent anion channel 1
  • voltage-dependent anion-selective channel protein 1

Background

VDAC1 is an outer membrane mitochondrial protein. The VDAC proteins are thought to form aqueous channels, or pores, through which adenine nucleotides cross the outer mitochondrial membrane. VDACs have been implicated in the formation of the mitochondrial permeability transition pore complex in apoptotic cells. This complex, formed by VDAC, adenine nucleotide translocator (ANT), and cyclophilin D (CypD), is thought to allow the mitochondria to undergo metabolic uncoupling and irreversible morphologic changes that ultimately destroy the mitochondria during apoptosis. VDACs are highly expressed in heart, liver and skeletal muscle, where concentrations of mitochondria are at their highest.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NBP3-42163
VDAC1 Antibody (C1)
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Bioinformatics

Gene Symbol VDAC1