Novus Biologicals products are now on bio-techne.com

ULBP-1 Antibody (170818) [Allophycocyanin]

Images

 
MOLT-4 human acute lymphoblastic leukemia cell line was stained with Mouse Anti-Human ULBP-1 APC-conjugated Monoclonal Antibody (Catalog # FAB1380A, filled histogram) or isotype control antibody (Catalog # IC003A, open ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
170818
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

ULBP-1 Antibody (170818) [Allophycocyanin] Summary

Immunogen
BaF3 mouse pro-B cell line transfected with human ULBP-1
Specificity
Stains human ULBP-1 cell transfectants. It does not stain cells transfected with ULBP-2 or ULBP-3.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
ULBP1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB1380A in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ULBP-1 Antibody (170818) [Allophycocyanin]

  • ALCAN-beta
  • MULT-1
  • N2DL1
  • N2DL-1
  • NKG2D ligand 1
  • NKG2DL
  • NKG2DL1
  • RAET1I
  • RAET1Ialcan-beta
  • Retinoic acid early transcript 1I
  • UL16 binding protein 1
  • UL16-binding protein 1
  • ULBP1
  • ULBP-1

Background

ULBP-1 is a member of a family of cell-surface proteins that function as ligands for human NKG2D. ULBP-1 has also been described under the names RaeT1I (Retinoic Acid Early Transcript), ALCAN-beta, and NKG2DL1. The name ULBP-1 derives from the original identification of three proteins, ULBP-1, -2, and -3, as ligands for the human cytomegalovirus glycoprotein UL16; they were designated UL16 Binding Proteins (ULBP). The gene for ULBP-1 resides in a cluster of ten related genes, six of which encode potentially functional glycoproteins. Amino acid sequence identity within this family ranges from 30-95%. These proteins are distantly related to MHC class I proteins, but they possess only the alpha 1 and alpha 2 Ig-like domains, and they have no capacity to bind peptide or interact with beta 2-microglobulin. They are anchored to the membrane via a GPI-linkage. ULBP-1 and several other family members are known to bind to human NKG2D, an activating receptor expressed on NK cells, NKT cells, gamma δ T cells, and CD8+ alpha beta T cells. Engagement of NKG2D results in the activation of cytolytic activity and/or cytokine production by these effector cells. ULBP-1 is expressed on some tumor cells and has been implicated in tumor surveillance (1-8).

  1. Cosman, D. et al. (2001) Immunity 14:123.
  2. Kubin, M. et al. (2001) Eur. J. Immunol. 31:1428.
  3. Sutherland, C. et al. (2002) J. Immunol. 168:671.
  4. Steinle, A. et al. (2001) Immunogenetics 53:279.
  5. Sutherland, C. et al. (2001) Immunol. Rev. 181:185
  6. Pende, D. et al. (2002) Cancer Res. 62:6178.
  7. Radosavljevic, M. et al. (2002) Genomics 79:114
  8. NKG2D and its Ligands, 2002; www.RnDSystems.com.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

MAB139
Species: Hu
Applications: CostimT, CyTOF-ready, Flow, Neut, WB
DY1298
Species: Hu
Applications: ELISA
MAB1517
Species: Hu
Applications: Block, CyTOF-ready, Flow
MAB1599
Species: Hu
Applications: CyTOF-ready, ELISA(Cap), ELISA(Det), ELISA(Sta), Flow, KO, WB
MAB6285
Species: Hu
Applications: CyTOF-ready, Flow, IHC, WB
AF2225
Species: Mu
Applications: AgAct, CyTOF-ready, Flow, IHC, WB
247-ILB
Species: Hu
Applications: BA
1849-NK
Species: Hu
Applications: BA
7149-UL
Species: Hu
Applications: BA
NBP1-49045
Species: Mu, Rt
Applications: Cell Depl, CyTOF-ready, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, InhibTFunc
NBP2-24653
Species: Hu, Mu, Rt
Applications: IHC, IHC-P, WB
NBP2-02541
Species: Hu, Pm, Mu, Pm, Rt
Applications: ICC/IF, IHC, IHC-P, WB
MAB97861
Species: Hu
Applications: Flow, IHC, IHC-P
NB120-6405
Species: Rt
Applications: B/N, CyTOF-ready, EM, ELISA, Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP
MAB666
Species: Hu
Applications: CyTOF-ready, Flow, Neut, WB
H00003126-P01
Species: Hu
Applications: ELISA, AP, PA, WB

Publications for ULBP-1 Antibody (FAB1380A)(7)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: Flow Cytometry, ICC.


Filter By Application
Flow Cytometry
(4)
ICC
(1)
All Applications
Filter By Species
Human
(5)
All Species
Showing Publications 1 - 7 of 7.
Publications using FAB1380A Applications Species
Zhao, NQ;Pi, R;Nguyen, DN;Ranganath, T;Seiler, C;Holmes, S;Marson, A;Blish, CA; NKp30 and NKG2D contribute to natural killer recognition of HIV-infected cells bioRxiv : the preprint server for biology 2024-06-27 [PMID: 38979175] (Flow Cytometry, Human) Flow Cytometry Human
Aublin-Gex, A;Jacolin, F;Diaz, O;Jacquemin, C;Marçais, A;Walzer, T;Lotteau, V;Vidalain, PO;Perrin-Cocon, L; Tethering of hexokinase 2 to mitochondria promotes resistance of liver cancer cells to natural killer cell cytotoxicity European journal of immunology 2024-06-04 [PMID: 38837415] (Flow Cytometry, Human) Flow Cytometry Human
Thi-Anh-Thuy Tran, Young-Hee Kim, Thi-Hoang-Oanh Duong, JayaLakshmi Thangaraj, Tan-Huy Chu, Shin Jung et al. Natural killer cell therapy potentially enhances the antitumor effects of bevacizumab plus irinotecan in a glioblastoma mouse model Frontiers in Immunology 2023-01-10 [PMID: 36703992]
Dario Gerace, Quan Zhou, Jennifer Hyoje-Ryu Kenty, Adrian Veres, Elad Sintov, Xi Wang et al. Engineering human stem cell-derived islets to evade immune rejection and promote localized immune tolerance Cell Reports Medicine 2023-01-17 [PMID: 36599351]
R Chimienti, T Baccega, S Torchio, F Manenti, S Pellegrini, A Cospito, A Amabile, MT Lombardo, P Monti, V Sordi, A Lombardo, M Malnati, L Piemonti Engineering of immune checkpoints B7-H3 and CD155 enhances immune compatibility of MHC-I-/- iPSCs for beta cell replacement Cell Reports, 2022-09-27;40(13):111423. 2022-09-27 [PMID: 36170817] (ICC, Human) ICC Human
X Zhong, H Liao, S Hu, K Luo, H Zhu The diterpenoid adenanthin upregulates the expression of natural killer group 2D receptor ligands in hepatocellular carcinoma cells Molecular and cellular probes, 2021-07-12;59(0):101759. 2021-07-12 [PMID: 34265372] (Flow Cytometry, Human) Flow Cytometry Human
AT Björklund, M Carlsten, E Sohlberg, LL Liu, T Clancy, M Karimi, S Cooley, JS Miller, M Klimkowska, M Schaffer, E Watz, KI Wikstrom, P Blomberg, BE Wahlin, M Palma, L Hansson, P Ljungman, E Hellström-, HG Ljunggren, KJ Malmberg Complete Remission with Reduction of High-risk Clones following Haploidentical NK Cell Therapy against MDS and AML Clin. Cancer Res., 2018-02-14;0(0):. 2018-02-14 [PMID: 29444931] (Flow Cytometry, Human) Flow Cytometry Human

Reviews for ULBP-1 Antibody (FAB1380A) (0)

There are no reviews for ULBP-1 Antibody (FAB1380A). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for ULBP-1 Antibody (FAB1380A) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.
Read our latest blog and use the new citation tool on bio-techne.com

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our ULBP-1 Antibody (170818) [Allophycocyanin] and receive a gift card or discount.

Bioinformatics

Gene Symbol ULBP1