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Troponin T type 1 (slow skeletal) Antibody

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Orthogonal Strategies: Immunohistochemistry-Paraffin: Troponin T type 1 (slow skeletal) Antibody [NBP2-38855] - Staining in human skeletal muscle and lymph node tissues using anti-TNNT1 antibody. Corresponding ...read more
Immunohistochemistry-Paraffin: Troponin T type 1 (slow skeletal) Antibody [NBP2-38855] - Staining of human kidney shows no positivity as expected.
Immunohistochemistry-Paraffin: Troponin T type 1 (slow skeletal) Antibody [NBP2-38855] - Staining of human skeletal muscle shows high expression.
Immunohistochemistry-Paraffin: Troponin T type 1 (slow skeletal) Antibody [NBP2-38855] - Staining of human lymph node shows no positivity as expected.
Immunohistochemistry-Paraffin: Troponin T type 1 (slow skeletal) Antibody [NBP2-38855] - Staining of human colon shows no positivity as expected.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

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Troponin T type 1 (slow skeletal) Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: EEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGE
Predicted Species
Mouse (97%), Rat (95%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TNNT1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Troponin T type 1 (slow skeletal) Recombinant Protein Antigen (NBP2-38855PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Troponin T type 1 (slow skeletal) Antibody

  • ANMtroponin T, slow skeletal muscle
  • FLJ98147
  • MGC104241
  • Slow skeletal muscle troponin T
  • STNT
  • TnTs
  • TNTtroponin T1, skeletal, slow
  • troponin T type 1 (skeletal, slow)
  • troponin-T1, skeletal, slow

Background

Troponin T type 1 encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TNNT1
Uniprot