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TRAILR1/TNFRSF10A Antibody (32A1380) [DyLight 594]

 
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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Simple Western, Flow, ICC/IF, CyTOF-ready
Clone
32A1380
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 594

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-27350AF350
Alexa Fluor 405
NBP2-27350AF405
Alexa Fluor 488
NBP2-27350AF488
Alexa Fluor 532
NBP2-27350AF532
Alexa Fluor 594
NBP2-27350AF594
Alexa Fluor 647
NBP2-27350AF647
Alexa Fluor 700
NBP2-27350AF700
Alexa Fluor 750
NBP2-27350AF750
Allophycocyanin
NBP2-27350APC
Allophycocyanin/Cy7
NB100-56747APCCY7
Biotin
NB100-56747B
DyLight 350
NBP2-27350UV
DyLight 405
NBP2-27350V
DyLight 488
NBP2-27350G
DyLight 550
NBP2-27350R
DyLight 650
NBP2-27350C
DyLight 680
NBP2-27350FR
DyLight 755
NBP2-27350IR
FITC
NBP2-27350F
HRP
NBP2-27350H
Janelia Fluor 549
NB100-56747JF549
Janelia Fluor 646
NB100-56747JF646
PE
NBP2-27350PE
PE/Atto594
NB100-56747PEATT594
PE/Cy5.5
NB100-56747PECY55
PE/Cy7
NB100-56747PECY7
PerCP
NBP2-27350PCP
Unconjugated
NB100-56747
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB100-56747
Azide and BSA Free
NBP2-27350
BSA Free
NB100-56747SS
BSA Free
NB100-56747
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TRAILR1/TNFRSF10A Antibody (32A1380) [DyLight 594] Summary

Immunogen
This monoclonal antibody was raised against a peptide corresponding to amino acid 2 to 21 of human DR4.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TNFRSF10A
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow (Cell Surface)
  • Flow (Intracellular)
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Simple Western
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for TRAILR1/TNFRSF10A Antibody (32A1380) [DyLight 594]

  • APO2
  • CD261 antigen
  • CD261
  • cytotoxic TRAIL receptor
  • Death receptor 4
  • DR4 TRAIL receptor 1
  • DR4
  • TNF-related apoptosis inducing ligand receptor 1
  • TNF-related apoptosis-inducing ligand receptor 1
  • TNFRSF10A
  • TRAIL R1
  • TRAILR1
  • TRAIL-R1
  • TRAILR-1
  • TRAILR1MGC9365
  • tumor necrosis factor receptor superfamily member 10A
  • tumor necrosis factor receptor superfamily, member 10a

Background

TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol TNFRSF10A