Species: Hu
Applications: WB, IHC, B/N
Host: Goat Polyclonal
Species: Hu
Applications: Flow, IHC, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: WB, Simple Western, Flow, ICC/IF, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Host: Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Description
TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Human
|
| Product By Gene ID |
8797 |
| Alternate Names |
- APO2
- CD261 antigen
- CD261
- cytotoxic TRAIL receptor
- Death receptor 4
- DR4 TRAIL receptor 1
- DR4
- TNF-related apoptosis inducing ligand receptor 1
- TNF-related apoptosis-inducing ligand receptor 1
- TRAIL-R1
- TRAILR-1
- TRAILR1MGC9365
- tumor necrosis factor receptor superfamily member 10A
- tumor necrosis factor receptor superfamily, member 10a
|
Research Areas for TRAILR1/TNFRSF10A
Find related products by research area and learn more about each of the different research areas below.
ApoptosisCancer
![Western Blot TRAILR1/TNFRSF10A Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/TRAIL_R1_AF347_Western_Blot_5303.jpg)
![Neutralization TRAILR1/TNFRSF10A Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/TRAIL_R1_AF347_Block_Neutralize_875.jpg)
![Immunohistochemistry TRAILR1/TNFRSF10A Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/TRAIL_R1_AF347_Immunohistochemistry_17355.jpg)
![Western Blot TRAILR1/TNFRSF10A Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af347_human-trail-r1-tnfrsf10a-affinity-purified-polyclonal-ab-8220249505980.jpg)
![Flow Cytometry TRAILR1/TNFRSF10A Antibody (69036) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/mab347_human-trailr1-tnfrsf10a-mab-clone-69036-flow-cytometry-412024133442.jpg)
![Immunohistochemistry TRAILR1/TNFRSF10A Antibody (69036) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/mab347_human-trail-r1-tnfrsf10a-mab-clone-69036-immunohistochemistry-187202416145..jpg)
![Sandwich ELISA TRAILR1/TNFRSF10A Antibody Pair [HRP]](http://images.novusbio.com/fullsize/TRAILR1-TNFRSF10A-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79599-img0001.jpg)
