Home » TR beta 1/NR1A2/Thyroid Hormone Receptor beta » Thyroid Hormone Receptor beta Antibodies » TR beta 1/NR1A2/Thyroid Hormone Receptor beta Antibody (H3825A) [Unconjugated]
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TR beta 1/NR1A2/Thyroid Hormone Receptor beta Antibody (H3825A) [Unconjugated]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP, ELISA
Clone
H3825A
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Suitable Sample Type
23015

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TR beta 1/NR1A2/Thyroid Hormone Receptor beta Antibody (H3825A) [Unconjugated] Summary

Immunogen
Recombinant human TR beta 1/NR1A2
aa 2-100
Specificity
This antibody specifically recognizes human TR beta 1, and does not cross-react with human TR beta 2 or human TR alpha. Not yet tested in other species.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
THRB
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunoprecipitation
  • Direct ELISA

Packaging, Storage & Formulations

Storage
This antibody is stable for greater than six months when held at -20 °C in a manual defrost freezer or at -70 °C. Upon thawing, the antibody can be stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Buffer
A liquid formulation in physiologic saline with 0.1% NaN3.
Preservative
0.1% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TR beta 1/NR1A2/Thyroid Hormone Receptor beta Antibody (H3825A) [Unconjugated]

  • avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2
  • c-erbA-2
  • c-erbA-beta
  • ERBA2MGC126109
  • ERBA-BETA
  • GRTH
  • MGC126110
  • NR1A2
  • NR1A2thyroid hormone receptor, beta (avian erythroblastic leukemia viral (v-erb-a)oncogene homolog 2)
  • Nuclear receptor subfamily 1 group A member 2
  • oncogene ERBA2
  • PRTH
  • THR1pituitary resistance to thyroid hormone
  • THRB
  • THRB1
  • THRB2
  • thyroid hormone receptor beta 1
  • thyroid hormone receptor beta
  • thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a)oncogene homolog 2, avian)
  • TR beta 1
  • v-ErbA2

Background

Thyroid Hormone Receptor beta (TR beta, THRB; NR1A2) is a member of the Nuclear Hormone Receptor superfamily. The ligands for TR beta are the thyroid hormones, which exist in two forms: T4 (3,5,3',5'-tetraiodo-L-thyronine) and T3 (3,5,3'-tri-iodo-L-thyronine). TR beta plays critical roles in the differentiation, growth, metabolism and physiology of a wide variety of tissues. The major partners of TRs are the Retinoid X Receptors (RXRs), which strongly enhance their ability to bind to specific DNA sequences and contribute to the specificity of TR.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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TR beta
1/NR1A2/Thyroid Hormo ...
PP-H3825A-00
TR beta 1/NR1A2/Thyroid Hormone Receptor beta Antibody (H3825A) [Unconjugated]
Species: Hu
Applications: WB, IP, ELISA

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Bioinformatics

Gene Symbol THRB