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TPX2 Antibody (TPX2-01) [Janelia Fluor® 525]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IP
Clone
TPX2-01
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 525

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-67265AF350
Alexa Fluor 405
NBP2-67265AF405
Alexa Fluor 488
NBP2-67265AF488
Alexa Fluor 532
NBP2-67265AF532
Alexa Fluor 594
NBP2-67265AF594
Alexa Fluor 647
NBP2-67265AF647
Alexa Fluor 700
NBP2-67265AF700
Alexa Fluor 750
NBP2-67265AF750
Allophycocyanin
NBP2-67265APC
Biotin
NBP2-67265B
CoraFluor 1
NBP2-67265CL1
DyLight 350
NBP2-67265UV
DyLight 405
NBP2-67265V
DyLight 488
NBP2-67265G
DyLight 550
NBP2-67265R
DyLight 594
NBP2-67265DL594
DyLight 650
NBP2-67265C
DyLight 680
NBP2-67265FR
DyLight 755
NBP2-67265IR
FITC
NBP2-67265F
HRP
NBP2-67265H
Janelia Fluor 549
NBP2-67265JF549
Janelia Fluor 646
NBP2-67265JF646
Janelia Fluor 669
NBP2-67265JF669
PE
NBP2-67265PE
PerCP
NBP2-67265PCP
Unconjugated
NBP2-67265
mFluor Violet 450 SE
NBP2-67265MFV450
mFluor Violet 500 SE
NBP2-67265MFV500
mFluor Violet 610 SE
NBP2-67265MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-67265
BSA Free
NBP2-67265
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TPX2 Antibody (TPX2-01) [Janelia Fluor® 525] Summary

Immunogen
Human TPX2
Specificity
The mouse monoclonal antibody TPX2-01 recognizes the epitope EPFVPKKEKKS (aa 636-646 in human) of TPX2, a microtubule-associated intracellular critical regulator of mitosis, which is overexpressed in many types of tumors and is a marker of worse prognosis in various cancers.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TPX2
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for TPX2 Antibody (TPX2-01) [Janelia Fluor® 525]

  • C20orf1HCTP4
  • C20orf2
  • chromosome 20 open reading frame 1
  • Differentially expressed in cancerous and non-cancerous lung cells 2
  • differentially expressed in lung cells
  • DIL2
  • DIL-2FLS353
  • HCA519
  • Hepatocellular carcinoma-associated antigen 519
  • P100
  • p100GD:C20orf1
  • preferentially expressed in colorectal cancer
  • Protein fls353
  • REPP86
  • restricted expression proliferation associated protein 100
  • Restricted expression proliferation-associated protein 100
  • targeting protein for Xklp2
  • TPX2, microtubule-associated protein homolog
  • TPX2, microtubule-associated, homolog (Xenopus laevis)

Background

TPX2 is a microtubule cross-linking protein involved in spindle formation. During mitosis, it is strictly associated with the mitotic spindle, whereas during phases S and G2 it is diffusely distributed throughout the nucleus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NBP2-67265JF525
TPX2 Antibody (TPX2-01) [Janelia Fluor® 525]
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IP

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Bioinformatics

Gene Symbol TPX2