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TIM-1/KIM-1/HAVCR Antibody [DyLight 755]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, KD
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 755

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-76701AF350
Alexa Fluor 405
NBP1-76701AF405
Alexa Fluor 488
NBP1-76701AF488
Alexa Fluor 532
NBP1-76701AF532
Alexa Fluor 594
NBP1-76701AF594
Alexa Fluor 647
NBP1-76701AF647
Alexa Fluor 700
NBP1-76701AF700
Alexa Fluor 750
NBP1-76701AF750
Biotin
NBP1-76701B
CoraFluor 1
NBP1-76701CL1
DyLight 350
NBP1-76701UV
DyLight 405
NBP1-76701V
DyLight 488
NBP1-76701G
DyLight 550
NBP1-76701R
DyLight 594
NBP1-76701DL594
DyLight 650
NBP1-76701C
DyLight 680
NBP1-76701FR
FITC
NBP1-76701F
HRP
NBP1-76701H
Janelia Fluor 525
NBP1-76701JF525
Janelia Fluor 549
NBP1-76701JF549
Janelia Fluor 646
NBP1-76701JF646
Janelia Fluor 669
NBP1-76701JF669
PerCP
NBP1-76701PCP
Unconjugated
NBP1-76701
mFluor Violet 450 SE
NBP1-76701MFV450
mFluor Violet 500 SE
NBP1-76701MFV500
mFluor Violet 610 SE
NBP1-76701MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-76701
BSA Free
NBP1-76701
BSA Free
NBP1-76701SS
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TIM-1/KIM-1/HAVCR Antibody [DyLight 755] Summary

Immunogen
Antibody was raised against a peptide corresponding to 16 amino acids near the amino terminus of human TIM-1. The immunogen is located within amino acids 50 - 100 of TIM-1. Amino Acid Squence: TNGTHVTYRKDTRYKL
Specificity
Human TIM-1/KIM-1/HAVCR has 5 isoforms, including isoform a precursor (364aa, 39kD), isoform a (364aa, 39kD), isoform b precursor (401aa, 44kD), isoform b (359aa, 39kD), and isoform c (359aa, 39kD). This antibody detects human isoform b precursor. Mouse TIM-1/KIM-1/HAVCR has 3 isoforms, including isoform a precursor (305aa, 33kD), isoform b precursor (282aa, 31kD) and isoform b (282aa, 31kD). Rat TIM-1/KIM-1/HAVCR has only one isoform identified so far (307aa, 34kD).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HAVCR1
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Knockdown Validated
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Mouse reactivity reported in (PMID: 29369823). Rat reactivity reported in (PMID: 30066041).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for TIM-1/KIM-1/HAVCR Antibody [DyLight 755]

  • CD365
  • HAVCR1
  • HAVCR-1
  • HAVCRT cell immunoglobin domain and mucin domain protein 1
  • hepatitis A virus cellular receptor 1
  • Kidney injury molecule 1
  • KIM1
  • KIM-1
  • T-cell immunoglobulin and mucin domain-containing protein 1
  • TIM1
  • TIM-1
  • TIM-1TIM
  • TIM1TIMD-1
  • TIMD1T-cell membrane protein 1

Background

TIM 1 is a transmembrane protein containing immunoglobulin domain and mucin-like domain; it is developmentally expressed at very high levels in the blastocyst. TIM 1 binds hepatitis virus in humans and is expressed on activated CD4+ lymphocytes especially on Th2 cells and has been implicated to play a critical role in the development of atopic disease (in particular airway hyperreactivity) and other Th2-biased immune responses.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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TIM-1/KIM-1/HAVCR
Antibody [DyLight 755 ...
NBP1-76701IR
TIM-1/KIM-1/HAVCR Antibody [DyLight 755]
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, KD

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol HAVCR1