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TIM-1/KIM-1/HAVCR Antibody [Alexa Fluor® 700]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, KD
Clonality
Polyclonal
Host
Rabbit
Conjugate
Alexa Fluor 700

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-76701AF350
Alexa Fluor 405
NBP1-76701AF405
Alexa Fluor 488
NBP1-76701AF488
Alexa Fluor 532
NBP1-76701AF532
Alexa Fluor 594
NBP1-76701AF594
Alexa Fluor 647
NBP1-76701AF647
Alexa Fluor 750
NBP1-76701AF750
Biotin
NBP1-76701B
CoraFluor 1
NBP1-76701CL1
DyLight 350
NBP1-76701UV
DyLight 405
NBP1-76701V
DyLight 488
NBP1-76701G
DyLight 550
NBP1-76701R
DyLight 594
NBP1-76701DL594
DyLight 650
NBP1-76701C
DyLight 680
NBP1-76701FR
DyLight 755
NBP1-76701IR
FITC
NBP1-76701F
HRP
NBP1-76701H
Janelia Fluor 525
NBP1-76701JF525
Janelia Fluor 549
NBP1-76701JF549
Janelia Fluor 646
NBP1-76701JF646
Janelia Fluor 669
NBP1-76701JF669
PerCP
NBP1-76701PCP
Unconjugated
NBP1-76701
mFluor Violet 450 SE
NBP1-76701MFV450
mFluor Violet 500 SE
NBP1-76701MFV500
mFluor Violet 610 SE
NBP1-76701MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-76701
BSA Free
NBP1-76701
BSA Free
NBP1-76701SS
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TIM-1/KIM-1/HAVCR Antibody [Alexa Fluor® 700] Summary

Immunogen
Antibody was raised against a peptide corresponding to 16 amino acids near the amino terminus of human TIM-1. The immunogen is located within amino acids 50 - 100 of TIM-1. Amino Acid Squence: TNGTHVTYRKDTRYKL
Specificity
Human TIM-1/KIM-1/HAVCR has 5 isoforms, including isoform a precursor (364aa, 39kD), isoform a (364aa, 39kD), isoform b precursor (401aa, 44kD), isoform b (359aa, 39kD), and isoform c (359aa, 39kD). This antibody detects human isoform b precursor. Mouse TIM-1/KIM-1/HAVCR has 3 isoforms, including isoform a precursor (305aa, 33kD), isoform b precursor (282aa, 31kD) and isoform b (282aa, 31kD). Rat TIM-1/KIM-1/HAVCR has only one isoform identified so far (307aa, 34kD).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HAVCR1
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Knockdown Validated
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Mouse reactivity reported in (PMID: 29369823). Rat reactivity reported in (PMID: 30066041).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for TIM-1/KIM-1/HAVCR Antibody [Alexa Fluor® 700]

  • CD365
  • HAVCR1
  • HAVCR-1
  • HAVCRT cell immunoglobin domain and mucin domain protein 1
  • hepatitis A virus cellular receptor 1
  • Kidney injury molecule 1
  • KIM1
  • KIM-1
  • T-cell immunoglobulin and mucin domain-containing protein 1
  • TIM1
  • TIM-1
  • TIM-1TIM
  • TIM1TIMD-1
  • TIMD1T-cell membrane protein 1

Background

TIM 1 is a transmembrane protein containing immunoglobulin domain and mucin-like domain; it is developmentally expressed at very high levels in the blastocyst. TIM 1 binds hepatitis virus in humans and is expressed on activated CD4+ lymphocytes especially on Th2 cells and has been implicated to play a critical role in the development of atopic disease (in particular airway hyperreactivity) and other Th2-biased immune responses.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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TIM-1/KIM-1/HAVCR
Antibody [Alexa Fluor ...
NBP1-76701AF700
TIM-1/KIM-1/HAVCR Antibody [Alexa Fluor® 700]
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, KD

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Bioinformatics

Gene Symbol HAVCR1