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Tie-2 Antibody [DyLight 755]

 
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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, Simple Western, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 755

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-69753AF350
Alexa Fluor 405
NBP1-69753AF405
Alexa Fluor 488
NBP1-69753AF488
Alexa Fluor 532
NBP1-69753AF532
Alexa Fluor 594
NBP1-69753AF594
Alexa Fluor 647
NBP1-69753AF647
Alexa Fluor 700
NBP1-69753AF700
Alexa Fluor 750
NBP1-69753AF750
Allophycocyanin
NBP1-69753APC
Biotin
NBP1-69753B
CoraFluor 1
NBP1-69753CL1
DyLight 350
NBP1-69753UV
DyLight 405
NBP1-69753V
DyLight 488
NBP1-69753G
DyLight 550
NBP1-69753R
DyLight 594
NBP1-69753DL594
DyLight 650
NBP1-69753C
DyLight 680
NBP1-69753FR
FITC
NBP1-69753F
HRP
NBP1-69753H
Janelia Fluor 525
NBP1-69753JF525
Janelia Fluor 549
NBP1-69753JF549
Janelia Fluor 585
NBP1-69753JF585
Janelia Fluor 635
NBP1-69753JF635
Janelia Fluor 646
NBP1-69753JF646
Janelia Fluor 669
NBP1-69753JF669
PE
NBP1-69753PE
PerCP
NBP1-69753PCP
Unconjugated
NBP1-69753
mFluor Violet 450 SE
NBP1-69753MFV450
mFluor Violet 500 SE
NBP1-69753MFV500
mFluor Violet 610 SE
NBP1-69753MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-69753
BSA Free
NBP1-69753SS
BSA Free
NBP1-69753
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Tie-2 Antibody [DyLight 755] Summary

Immunogen
A genomic peptide made to an internal region of the human TIE2 protein (within residues 250-400). [Swiss-Prot Q02763]
Localization
Membrane, single pass type-1 membrane protein
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TEK
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Simple Western
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Tie-2 Antibody [DyLight 755]

  • angiopoietin-1 receptor
  • CD202b antigen
  • CD202b
  • EC 2.7.10
  • EC 2.7.10.1
  • hTIE2
  • p140 TEK
  • soluble TIE2 variant 1
  • soluble TIE2 variant 2
  • TEK tyrosine kinase, endothelial
  • TEK
  • Tie2
  • Tie-2
  • TIE2CD202b
  • Tunica interna endothelial cell kinase
  • Tyrosine-protein kinase receptor TEK
  • Tyrosine-protein kinase receptor TIE-2
  • venous malformations, multiple cutaneous and mucosal
  • VMCM
  • VMCM1

Background

TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin like loops separated by three epidermal growth factor like repeats that are connected to three fibronectin type III like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations; the TIE2 signaling pathway appears to be critical for endothelial cell smooth muscle cell communication in venous morphogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Applications: IHC, IHC-Fr, IHC-P, WB

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TEK