Thymidylate Synthase Antibody (TS106)

Thymidylate synthase (TS) is an intracellular enzyme critical for de novo synthesis of DNA. In cancer, expression of TS is often elevated and becomes further elevated as a result of treatment with the most commonly used chemotherapeutic, 5-fluorouracil (5-FU). Resistance or lack of response to 5-FU is attributed to the elevation of TS activity. Overexpression of TS has been demonstrated in many types of tumors including breast, colon, gastric and melanoma and is usually predictive of shortened survival time.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC-P.

Showing Publication 1 - 1 of 1.

Publication using NBP2-34445	Applications	Species
Hendrych M, RihovA K, Adamova B et al. Disulfiram increases the efficacy of 5-fluorouracil in organotypic cultures of colorectal carcinoma Biomedicine & Pharmacotherapy 2022-09-01 [PMID: 36076577] (IHC-P, Human)	IHC-P	Human

Array NBP2-34445

• Thymidylate Synthase Antibodies
• Thymidylate Synthase ELISA Kits
• Thymidylate Synthase Lysate
• Thymidylate Synthase Proteins