Thioredoxin Reductase 1/TRXR1 Antibody

This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. [provided by RefSeq]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 application: WB.

Showing Publication 1 - 1 of 1.

Publication using NBP2-20620	Applications	Species
Seale LA, Ha HY, Hashimoto AC et al. Relationship between selenoprotein P and selenocysteine lyase: Insights into selenium metabolism. Free Radic Biol Med 2018-03-20 [PMID: 29567390] (WB)	WB

Array NBP2-20620

• Thioredoxin Reductase 1/TRXR1 Antibodies
• Thioredoxin Reductase 1/TRXR1 ELISA Kits
• Thioredoxin Reductase 1/TRXR1 Lysate
• Thioredoxin Reductase 1/TRXR1 Proteins