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Thioredoxin Reductase 1/TRXR1 Antibody

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Orthogonal Strategies: Western Blot: Thioredoxin Reductase 1/TRXR1 Antibody [NBP1-81791] - Analysis in human cell lines PC-3 and MCF-7 using Anti-TXNRD1 antibody. Corresponding TXNRD1 RNA-seq data are presented ...read more
Immunohistochemistry-Paraffin: Thioredoxin Reductase 1/TRXR1 Antibody [NBP1-81791] - Staining of human testis shows strong cytoplasmic and nuclear positivity in Leydig cells and basal cells in the seminiferous ducts.
Western Blot: Thioredoxin Reductase 1/TRXR1 Antibody [NBP1-81791] - Lane 1: Marker [kDa] 219, 112, 85, 49, 32, 25, 18. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human cell line ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

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Thioredoxin Reductase 1/TRXR1 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: SCEDGRALEGTLSELAAETDLPVVFVKQRKIGGHGPTLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYG
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TXNRD1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Thioredoxin Reductase 1/TRXR1 Protein (NBP1-81791PEP)
Publications
Read Publication using NBP1-81791.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Thioredoxin Reductase 1/TRXR1 Antibody

  • EC 1.8.1
  • EC 1.8.1.9
  • Gene associated with retinoic and IFN-induced mortality 12 protein
  • Gene associated with retinoic and interferon-induced mortality 12 protein
  • GRIM12
  • GRIM-12
  • GRIM-12TR1
  • KDRF
  • KM-102-derived reductase-like factor
  • MGC9145
  • oxidoreductase
  • Thioredoxin Reductase 1
  • thioredoxin reductase 1, cytoplasmic
  • thioredoxin reductase GRIM-12
  • Thioredoxin reductase TR1
  • TR
  • TR1
  • TRXR1
  • TRXRD1
  • TXNR
  • TXNRD1
  • TXNRTRXR1

Background

thioredoxin reductase 1 is a pyridine nucleotide oxidoreductase which reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. It is thought to function as a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine residue which is required for the catalytic activity. Alternative splicing results in several transcript variants encoding the same protein. Additional transcript variants have been described but their biological validity has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Thioredoxin Reductase 1/TRXR1 Antibody (NBP1-81791)(1)

We have publications tested in 1 application: WB.


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Bioinformatics

Gene Symbol TXNRD1