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Thioredoxin Reductase 1/TRXR1 Antibody - BSA Free

Images

 
Western Blot: Thioredoxin Reductase 1/TRXR1 Antibody [NBP1-33210] - Sample (30 ug of whole cell lysate) A: A431 7. 5% SDS PAGE; antibody diluted at 1:1000.
Immunohistochemistry-Paraffin: Thioredoxin Reductase 1/TRXR1 Antibody [NBP1-33210] - Human hepatoma, dilution: 1:500. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.
Western Blot: Thioredoxin Reductase 1/TRXR1 Antibody [NBP1-33210] - Mouse liver lysate/extract 7. 5 % SDS-PAGE gel, antibody dilution 1:1000.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free

Order Details

Thioredoxin Reductase 1/TRXR1 Antibody - BSA Free Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human Thioredoxin Reductase 1/TRXR1. The exact sequence is proprietary.
Localization
Cytoplasm, Isoform 4: Cytoplasm, Nucleus, Isoform 5: Cytoplasm
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TXNRD1
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
Theoretical MW
71 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris-Glycine (pH7), 10% Glycerol
Preservative
0.01% Thimerosal
Purity
Antigen Affinity-purified

Alternate Names for Thioredoxin Reductase 1/TRXR1 Antibody - BSA Free

  • EC 1.8.1
  • EC 1.8.1.9
  • Gene associated with retinoic and IFN-induced mortality 12 protein
  • Gene associated with retinoic and interferon-induced mortality 12 protein
  • GRIM12
  • GRIM-12
  • GRIM-12TR1
  • KDRF
  • KM-102-derived reductase-like factor
  • MGC9145
  • oxidoreductase
  • Thioredoxin Reductase 1
  • thioredoxin reductase 1, cytoplasmic
  • thioredoxin reductase GRIM-12
  • Thioredoxin reductase TR1
  • TR
  • TR1
  • TRXR1
  • TRXRD1
  • TXNR
  • TXNRD1
  • TXNRTRXR1

Background

This protein is a pyridine nucleotide oxidoreductase which reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. It is thought to function as a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine residue which is required for the catalytic activity. Alternative splicing results in several transcript variants encoding the same protein. Additional transcript variants have been described but their biological validity has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Bioinformatics

Gene Symbol TXNRD1