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Thioredoxin Reductase 1/TRXR1 Antibody (489804) [Alexa Fluor® 532]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, CyTOF-ready, Flow
Clone
489804
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 532

Order Details

Thioredoxin Reductase 1/TRXR1 Antibody (489804) [Alexa Fluor® 532] Summary

Immunogen
E. coli-derived recombinant mouse Thioredoxin Reductase 1/TRXR1
Met1-Ile497
Accession # Q16881
Specificity
Detects mouse Thioredoxin Reductase 1/TRXR1 in direct ELISAs and human, mouse, and rat Thioredoxin Reductase 1/TRXR1 in Western blots.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TXNRD1
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Intracellular Staining by Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Thioredoxin Reductase 1/TRXR1 Antibody (489804) [Alexa Fluor® 532]

  • EC 1.8.1
  • EC 1.8.1.9
  • Gene associated with retinoic and IFN-induced mortality 12 protein
  • Gene associated with retinoic and interferon-induced mortality 12 protein
  • GRIM12
  • GRIM-12
  • GRIM-12TR1
  • KDRF
  • KM-102-derived reductase-like factor
  • MGC9145
  • oxidoreductase
  • Thioredoxin Reductase 1
  • thioredoxin reductase 1, cytoplasmic
  • thioredoxin reductase GRIM-12
  • Thioredoxin reductase TR1
  • TR
  • TR1
  • TRXR1
  • TRXRD1
  • TXNR
  • TXNRD1
  • TXNRTRXR1

Background

thioredoxin reductase 1 is a pyridine nucleotide oxidoreductase which reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. It is thought to function as a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine residue which is required for the catalytic activity. Alternative splicing results in several transcript variants encoding the same protein. Additional transcript variants have been described but their biological validity has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TXNRD1