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TC10 Antibody - Azide and BSA Free

Images

 
Western Blot: TC10 Antibody [H00023433-B01P] - Analysis of RHOQ expression in transfected 293T cell line by RHOQ polyclonal antibody. Lane 1: RHOQ transfected lysate(22.55 KDa). Lane 2: Non-transfected lysate.
Immunocytochemistry/ Immunofluorescence: TC10 Antibody [H00023433-B01P] - Analysis of purified antibody to RHOQ on HeLa cell. (antibody concentration 10 ug/ml)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Mouse
Conjugate
Unconjugated
Format
Azide and BSA Free

Order Details

TC10 Antibody - Azide and BSA Free Summary

Immunogen
RHOQ (NP_036381.2, 1 a.a. - 205 a.a.) full-length human protein. MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIGTQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAIIAILTPKKHTVKKRIGSRCINCCLIT
Isotype
IgG
Clonality
Polyclonal
Host
Mouse
Gene
RHOQ
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
This antibody is useful for Western Blot, Functional, Immunofluorescence

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for TC10 Antibody - Azide and BSA Free

  • ARHQTC10A
  • ras homolog gene family, member Q
  • Ras-like protein family member 7A
  • Ras-like protein TC10
  • RAS-like, family 7, member A
  • rho-related GTP-binding protein RhoQ
  • TC10RASL7A

Background

TC10 is a member of the Rho family of GTP-binding proteins and is closely related to Cdc42 and Rac 1. Cycling between inactive and active GTP-bound state, active TC10 can directly interact with Cdc42 kinase, p21-activated protein kinases as well as other kinases (1). Constitutive expression of active TC10 mutants (TC10/Q75L) in fibroblast decrease actin stress fiber and formation of plasma membrane microspikes, while wild type TC10 has no effect on fibroblast cell morphology (2). Mostly expressed in adipose and muscle tissues, TC10 has been found to be activated by C3G (from the insulin pathway) in adipocytes (3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol RHOQ
Uniprot