| Reactivity | HuSpecies Glossary |
| Applications | IHC |
| Clone | STAR/2077 |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugate | DyLight 550 |
| Immunogen | Recombinant fragment (around aa 39-108) of human StAR protein (exact sequence is proprietary) (Uniprot: P49675) |
| Localization | Cytoplasmic (Mitochondria) |
| Marker | Leydig Cell Marker |
| Specificity | Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone. It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas. |
| Isotype | IgG2b Kappa |
| Clonality | Monoclonal |
| Host | Mouse |
| Gene | STAR |
| Purity | Protein A or G purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
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| Application Notes | Optimal dilution of this antibody should be experimentally determined. |
| Storage | Store at 4C in the dark. |
| Buffer | 50mM Sodium Borate |
| Preservative | 0.05% Sodium Azide |
| Purity | Protein A or G purified |
![StAR Antibody (STAR/2077) [DyLight 550]](/sites/all/modules/enterprise-tech/et_datasheets/images/novus_guarantee.png "StAR Antibody (STAR/2077) [DyLight 550]")
Secondary Antibodies |
Isotype Controls |
Research Areas for StAR Antibody (NBP3-08547R)Find related products by research area.
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| Gene Symbol | STAR |
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