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SP-B/Surfactant Protein B Antibody

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Immunohistochemistry-Paraffin: SP-B/Surfactant Protein B Antibody [NBP2-49359] - Staining in human lung and kidney tissues using anti-SFTPB antibody. Corresponding SFTPB RNA-seq data are presented for the same tissues.
Orthogonal Strategies: Immunohistochemistry-Paraffin: SP-B/Surfactant Protein B Antibody [NBP2-49359] - Staining in human lung and kidney tissues using anti-SFTPB antibody. Corresponding SFTPB RNA-seq data are ...read more
Immunohistochemistry-Paraffin: SP-B/Surfactant Protein B Antibody [NBP2-49359] - Staining of human lung shows high expression.
Immunohistochemistry-Paraffin: SP-B/Surfactant Protein B Antibody [NBP2-49359] - Staining of human kidney shows low expression as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

  

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SP-B/Surfactant Protein B Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: PLVIDYFQNQIDSNGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPLPDPLLDKLVLPVLPGALQARPGPHTQDLS
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SFTPB
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
SP-B/Surfactant Protein B Recombinant Protein Antigen (NBP2-49359PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for SP-B/Surfactant Protein B Antibody

  • 18 kDa pulmonary-surfactant protein
  • 6 kDa protein
  • PSP-B
  • pulmonary surfactant-associated protein B
  • Pulmonary surfactant-associated proteolipid SPL(Phe)
  • SFTB3
  • SFTP3
  • SFTPB
  • SMDP1
  • SP-B surfactant, pulmonary-associated protein B
  • SP-B
  • surfactant protein B

Background

The SFTPB gene encodes the pulmonary-associated surfactant B protein (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a lipid-rich material that prevents lung collapse by lowering surface tension at the air-liquid interface in the alveoli of lung. SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Surfactant is composed of phospholipids and other surfactant-associated proteins (Clark et al., 1995 [PubMed 7644495]). See also SFTPA1 (MIM 178630), SFTPC (MIM 178620), and SFTPD (MIM 178635).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SFTPB