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Somatostatin R5/SSTR5 Antibody

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Western Blot: Somatostatin R5/SSTR5 Antibody [NB100-56498] - Analysis of Somatostatin R5/SSTR5 in human pancreas lysate in the 1) absence and 2) presence of immunizing peptide using Somatostatin Receptor 5 antibody at ...read more
Immunohistochemistry-Paraffin: Somatostatin R5/SSTR5 Antibody [NB100-56498] - Analysis of human placenta using Somatostatin Receptor 5 antibody at 10 ug/ml.

Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

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Somatostatin R5/SSTR5 Antibody Summary

Immunogen
A portion of amino acids 300-350 of human SSTR5 was used as the immunogen.
Predicted Species
Primate (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SSTR5
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 10 ug/ml
  • Immunohistochemistry-Paraffin 10 ug/ml
  • Western Blot 0.25 ug/ml
Application Notes
The expected size of SSRT5, based on amino acid content, is approximately 40 kD. It is believed that the 5-10 kD increase in observed size is due to glycosylation.
Control
Human Pancreas Whole Tissue Lysate (Adult Whole Normal)

Reactivity Notes

The Somatostatin Receptor 5 amino acid sequence used as immunogen for this antibody is 94% in chimpanzee.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS containing 0.2% gelatin
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Somatostatin R5/SSTR5 Antibody

  • Somatostatin R5
  • somatostatin receptor 5
  • somatostatin receptor subtype 5
  • somatostatin receptor type 5
  • SomatostatinR5
  • SS5R
  • SS-5-R
  • SS5-R
  • SST5
  • SSTR5

Background

Official Gene Symbol: SSTR5 Gen Bank Accession Number: NP_001044 Gene ID: 6755 (human) Gene Map Locus: 16p13.3 (human) Somatostatin is a multifunctional protein affecting exocrine and endocrine protein secretion, neurotransmission, and neuronal modulation and regulating cell proliferation. All these functions of Somatostatin are executed through a class of GPCR protein family members called somatostatin receptor. Till date, 6 classes of somatostatin receptors have been discovered out of which SSTR5, 364A.A protein, is a receptor subtype expressed predominantly in the pituitary and hypothalamus region of brain. Studies revealed that SSTR5 contains seven transmembrane regions and undergoes homodimerization and also heterodimerizes with SSTR1. Although the specific functions of SSTR5 are still elusive, the studies indicate that it complements SSTR2 regulation of ACTH secretion. Polymorphisms in SSTR5 gene have been observed in patients with acromegaly.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SSTR5
Uniprot