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SLC31A1/CTR1 Antibody (5E6.1B4) [Janelia Fluor® 635]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
5E6.1B4
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 635

Order Details

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SLC31A1/CTR1 Antibody (5E6.1B4) [Janelia Fluor® 635] Summary

Immunogen
Two synthetic peptides made to internal sequences of human SLC31A1/CTR1 protein (sequences found between amino acids 50-150) [UniProt# O15431]
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
SLC31A1
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Use in Mouse reported in scientific literature (PMID:32060280).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for SLC31A1/CTR1 Antibody (5E6.1B4) [Janelia Fluor® 635]

  • Copper transporter 1
  • COPT1
  • COPT1high affinity copper uptake protein 1
  • CTR1
  • CTR1MGC75487
  • HCTR1
  • hCTR1copper transport 1 homolog
  • SLC31A1
  • solute carrier family 31 (copper transporters), member 1
  • Solute carrier family 31 member 1

Background

SLC31A1/CTR1 (High affinity copper uptake protein 1) is a 190 amino acid cell membrane protein. SLC31A1 forms a homotrimer and is a high-affinity copper transporter. It functions in the uptake of dietary copper. It may play a role in infection by chimpanzee endogenous retrovirus 2, Wilson disease, Menkes disease, ovarian carcinoma, ovarian cancer, prostate cancer, ethylmalonic encephalopathy, esophageal squamous cell carcinoma, cleft lip, squamous cell carcinoma and T-cell deficiency.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for SLC31A1/CTR1 Antibody (NBP2-36573JF635) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for SLC31A1/CTR1 Antibody (NBP2-36573JF635)

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Blogs on SLC31A1/CTR1.

SLC31A1/CTR1 - a copper transporter with important implications for platinum-based chemotherapy
Copper is an essential micronutrient that serves as a cofactor in numerous biological processes, but can be toxic when present in excess. Because of this, cells must tightly maintain copper levels. This includes balance between import and export of...  Read full blog post.

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Bioinformatics

Gene Symbol SLC31A1