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SLC31A1/CTR1 Antibody (5E6.1B4) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Po, PmSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
5E6.1B4
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 549

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-36573AF350
Alexa Fluor 405
NBP2-36573AF405
Alexa Fluor 488
NBP2-36573AF488
Alexa Fluor 532
NBP2-36573AF532
Alexa Fluor 594
NBP2-36573AF594
Alexa Fluor 647
NBP2-36573AF647
Alexa Fluor 700
NBP2-36573AF700
Alexa Fluor 750
NBP2-36573AF750
Biotin
NBP2-36573B
CoraFluor 1
NBP2-36573CL1
DyLight 350
NBP2-36573UV
DyLight 405
NBP2-36573V
DyLight 488
NBP2-36573G
DyLight 550
NBP2-36573R
DyLight 594
NBP2-36573DL594
DyLight 650
NBP2-36573C
DyLight 680
NBP2-36573FR
DyLight 755
NBP2-36573IR
FITC
NBP2-36573F
HRP
NBP2-36573H
Janelia Fluor 525
NBP2-36573JF525
Janelia Fluor 585
NBP2-36573JF585
Janelia Fluor 635
NBP2-36573JF635
Janelia Fluor 646
NBP2-36573JF646
Janelia Fluor 669
NBP2-36573JF669
Unconjugated
NBP2-36573
mFluor Violet 450 SE
NBP2-36573MFV450
mFluor Violet 500 SE
NBP2-36573MFV500
mFluor Violet 610 SE
NBP2-36573MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-36573
BSA Free
NBP2-36573SS
BSA Free
NBP2-36573
Azide and BSA Free
NBP2-80951
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SLC31A1/CTR1 Antibody (5E6.1B4) [Janelia Fluor® 549] Summary

Immunogen
Two synthetic peptides made to internal sequences of human SLC31A1/CTR1 protein (sequences found between amino acids 50-150) [UniProt# O15431]
Predicted Species
Rat (96%), Porcine (96%), Primate (100%). Backed by our 100% Guarantee.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
SLC31A1
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Use in Mouse reported in scientific literature (PMID:32060280).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for SLC31A1/CTR1 Antibody (5E6.1B4) [Janelia Fluor® 549]

  • Copper transporter 1
  • COPT1
  • COPT1high affinity copper uptake protein 1
  • CTR1
  • CTR1MGC75487
  • HCTR1
  • hCTR1copper transport 1 homolog
  • SLC31A1
  • solute carrier family 31 (copper transporters), member 1
  • Solute carrier family 31 member 1

Background

SLC31A1/CTR1 (High affinity copper uptake protein 1) is a 190 amino acid cell membrane protein. SLC31A1 forms a homotrimer and is a high-affinity copper transporter. It functions in the uptake of dietary copper. It may play a role in infection by chimpanzee endogenous retrovirus 2, Wilson disease, Menkes disease, ovarian carcinoma, ovarian cancer, prostate cancer, ethylmalonic encephalopathy, esophageal squamous cell carcinoma, cleft lip, squamous cell carcinoma and T-cell deficiency.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NBP2-36573JF549
SLC31A1/CTR1 Antibody (5E6.1B4) [Janelia Fluor® 549]
Species: Hu, Mu, Rt, Po, Pm
Applications: WB, ICC/IF, IHC

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Secondary Antibodies

 

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SLC31A1/CTR1 - a copper transporter with important implications for platinum-based chemotherapy
Copper is an essential micronutrient that serves as a cofactor in numerous biological processes, but can be toxic when present in excess. Because of this, cells must tightly maintain copper levels. This includes balance between import and export of...  Read full blog post.
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Bioinformatics

Gene Symbol SLC31A1