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Serpin C1/Antithrombin-III Antibody (2B12)

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Western Blot: Serpin C1/Antithrombin-III Antibody (2B12) [H00000462-M02] - Analysis of SERPINC1 expression in transfected 293T cell line by SERPINC1 monoclonal antibody (M02), clone 2B12.Lane 1: SERPINC1 transfected lysate(29.1 KDa).Lane 2: Non-transfected lysate.
Western Blot: Serpin C1/Antithrombin-III Antibody (2B12) [H00000462-M02] - Analysis of SERPINC1 expression in transfected 293T cell line by SERPINC1 monoclonal antibody (M02), clone 2B12.Lane 1: SERPINC1 transfected ...read more
Western Blot: Serpin C1/Antithrombin-III Antibody (2B12) [H00000462-M02] - SERPINC1 monoclonal antibody (M02), clone 2B12. Analysis of SERPINC1 expression in human kidney.
Sandwich ELISA: Serpin C1/Antithrombin-III Antibody (2B12) [H00000462-M02] - Detection limit for recombinant GST tagged SERPINC1 is 3 ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
2B12
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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Serpin C1/Antithrombin-III Antibody (2B12) Summary

Description
Quality control test: Antibody Reactive Against Recombinant Protein.
Immunogen
SERPINC1 (AAH22309.1, 1 a.a. ~ 259 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MYSNVIGTVTSGKRKVYLLSLLLIGFWDCVTCHGSPVDICTAEPRDIPMNPMCIYRSPEKKATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANPCVK
Specificity
SERPINC1 - serpin peptidase inhibitor, clade C (antithrombin), member 1 (2B12)
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
SERPINC1
Purity
Ascites
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Applications/Dilutions

Dilutions
  • ELISA
  • Sandwich ELISA
  • Western Blot 1:500
Application Notes
Antibody reactivity against transfected lysate and recombinant protein for WB. It has been used for ELISA.
Publications
Read Publication using H00000462-M02.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
Ascites

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Serpin C1/Antithrombin-III Antibody (2B12)

  • Antithrombin-III
  • AT3antithrombin-III
  • ATIII
  • ATIIIantithrombin III
  • MGC22579
  • serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
  • serine-cysteine proteinase inhibitor clade C member 1
  • Serpin C1
  • serpin peptidase inhibitor, clade C (antithrombin), member 1

Background

Antithrombin III (ATH III) is a plasma protein synthesised in the liver. Normal plasma levels are 115 to 160mg/L. ATH III consists of a single polypeptide chain and has a molecular weight of 58kDa. ATH III is a serine protease inhibitor and regulates coagulation by the formation of covalently liked complexes. ATH III also has a heparin binding site and in the presence of heparin the inhibition of thrombin, factors IXa, Xa and XIa is enhanced 1000 fold. Low levels of ATH III (functional or concentration) are associated with deep vein thrombosis and pulmonary embolism. Antithrombin assays are based on immunologic, enzymatic, or clotting properties

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SERPINC1
OMIM