Serpin C1/Antithrombin-III Products

Description

Antithrombin III (ATH III) is a plasma protein synthesised in the liver. Normal plasma levels are 115 to 160mg/L. ATH III consists of a single polypeptide chain and has a molecular weight of 58kDa. ATH III is a serine protease inhibitor and regulates coagulation by the formation of covalently liked complexes. ATH III also has a heparin binding site and in the presence of heparin the inhibition of thrombin, factors IXa, Xa and XIa is enhanced 1000 fold. Low levels of ATH III (functional or concentration) are associated with deep vein thrombosis and pulmonary embolism. Antithrombin assays are based on immunologic, enzymatic, or clotting properties

Bioinformatics

Entrez	11905 Mouse 304917 Rat 462 Human
Uniprot	AAH22309 Human AAH22309.1 Human NM_000488 Human P01008 Human P32261 Mouse
Product By Gene ID	462
Alternate Names	AT3antithrombin-III ATIIIantithrombin III MGC22579 serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1 serine-cysteine proteinase inhibitor clade C member 1 Serpin C1 serpin peptidase inhibitor, clade C (antithrombin), member 1