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Serpin C1/Antithrombin-III Antibody (208730)

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB
Clone
208730
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Formulation Size Price
Carrier Free
MAB1287-SP
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Serpin C1/Antithrombin-III Antibody (208730) Summary

Specificity
Detects mouse Serpin C1/Antithrombin-III in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross‑reactivity with recombinant human (rh) Serpin C1 is observed and no cross-reactivity with rhSerpin A1, A3, F2, recombinant mouse Serpin D1 or A5 is observed.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
SERPINC1
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Applications/Dilutions

Dilutions
  • Western Blot 1 ug/mL
Publications
Read Publications using
MAB1287 in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. See Certificate of Analysis for details.
*Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Serpin C1/Antithrombin-III Antibody (208730)

  • Antithrombin-III
  • AT3antithrombin-III
  • ATIII
  • ATIIIantithrombin III
  • MGC22579
  • serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
  • serine-cysteine proteinase inhibitor clade C member 1
  • Serpin C1
  • serpin peptidase inhibitor, clade C (antithrombin), member 1

Background

Serpin C1, also called Antithrombin-III, is the principal plasma serpin that inhibits blood clotting proteases such as thrombin and factor Xa.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Serpin C1/Antithrombin-III Antibody (MAB1287)(5)

We have publications tested in 2 confirmed species: Human, Hamster.

We have publications tested in 3 applications: Flow Cytometry, Functional Assay, Western Blot.


Filter By Application
Flow Cytometry
(1)
Functional Assay
(2)
Western Blot
(2)
All Applications
Filter By Species
Human
(3)
Hamster
(1)
All Species
Showing Publications 1 - 5 of 5.
Publications using MAB1287 Applications Species
R Karlsson, P Chopra, A Joshi, Z Yang, SY Vakhrushev, TM Clausen, CD Painter, GP Szekeres, YH Chen, DR Sandoval, L Hansen, JD Esko, K Pagel, DP Dyer, JE Turnbull, H Clausen, GJ Boons, RL Miller Dissecting structure-function of 3-O-sulfated heparin and engineered heparan sulfates Science Advances, 2021-12-22;7(52):eabl6026. 2021-12-22 [PMID: 34936441] (Flow Cytometry, Hamster) Flow Cytometry Hamster
Higgins NR, Greenslade JE, Wu JJ et al. Serpin neuropathology in the P497S UBQLN2 mouse model of ALS/FTD Brain pathology (Zurich, Switzerland) 3/29/2021 [PMID: 33780087]
E Barbon, G Ayme, A Mohamadi, JF Ottavi, C Kawecki, C Casari, S Verhenne, S Marmier, L van Witten, S Charles, F Collaud, CV Denis, OD Christophe, F Mingozzi, PJ Lenting Single-domain antibodies targeting antithrombin reduce bleeding in hemophilic mice with or without inhibitors EMBO Mol Med, 2020-03-11;0(0):e11298. 2020-03-11 [PMID: 32159286] (Western Blot, Human) Western Blot Human
Dower K, Ellis DK, Saraf K, Jelinsky SA, Lin LL Innate immune responses to TREM-1 activation: overlap, divergence, and positive and negative cross-talk with bacterial lipopolysaccharide. J. Immunol., 2008-03-01;180(5):3520-34. 2008-03-01 [PMID: 18292579] (Functional Assay, Human) Functional Assay Human
Gibot S, Kolopp-Sarda MN, Bollaert PE, Lozniewski A, Mory F, Levy B, Faure GC A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis. J. Exp. Med., 2004-11-22;200(11):1419-26. 2004-11-22 [PMID: 15557347] (Functional Assay, Western Blot, Human) Functional Assay, Western Blot Human

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Product General Protocols

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Video Protocols

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FAQs for Serpin C1/Antithrombin-III Antibody (MAB1287) (0)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol SERPINC1
Uniprot