Rat Serpin A8/Angiotensinogen ELISA Kit (Chemiluminescence)

Angiotensin II is encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Showing Publication 1 - 1 of 1.

Publication using NBP2-66668	Applications	Species
Sun H, Hodgkinson CP, Pratt RE, Dzau VJ CRISPR/Cas9 Mediated Deletion of the Angiotensinogen Gene Reduces Hypertension: A Potential for Cure? Hypertension (Dallas, Tex. : 1979) 2021-04-05 [PMID: 33813849]

Array NBP2-66668

• Serpin A8/Angiotensinogen Antibodies
• Serpin A8/Angiotensinogen Antibody Pair
• Serpin A8/Angiotensinogen ELISA Kits
• Serpin A8/Angiotensinogen Lysate
• Serpin A8/Angiotensinogen Proteins
• Serpin A8/Angiotensinogen ELISA