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Serpin A7/TBG Antibody [mFluor Violet 610 SE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
mFluor Violet 610 SE

Order Details

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Serpin A7/TBG Antibody [mFluor Violet 610 SE] Summary

Immunogen
Produced in rabbits immunized with purified, recombinant Human Serpin A7/TBG (Accession#: NP_000345.2; Met 1-Ala 415)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SERPINA7
Purity
Antigen and protein A Affinity-purified
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Applications/Dilutions

Dilutions
  • ELISA
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Serpin A7/TBG Antibody [mFluor Violet 610 SE]

  • antitrypsin), member 7
  • FLJ17820
  • member 7
  • Serpin A7
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)
  • T4-binding globulin
  • TBG
  • TBGclade A (alpha-1 antiproteinase
  • thyroxin-binding globulin
  • thyroxine-binding globulin

Background

Thyroxine Binding Globulin (TBG) is one of three proteins responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3 triiodothyronine (T3) in the bloodstream, along with transthyretin and albumin. TBG has the highest affinity for T4 and T3, but is present in the lowest concentration of the three proteins. Despite its low concentration, TBG carries the majority of T4 in serum. Due to the very low serum concentration of T4 & T3, TBG is rarely more than 25% saturated with ligand. Unlike transthyretin and albumin, TBG has a single binding site for T4/T3. Genomically, TBG is a serpin, although it has no inhibitory function like many other members of this class of proteins. TBG is synthesized primarily in the liver.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SERPINA7