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Serpin A7/TBG Antibody [CoraFluor™ 1]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-99678AF350
Alexa Fluor 405
NBP2-99678AF405
Alexa Fluor 488
NBP2-99678AF488
Alexa Fluor 532
NBP2-99678AF532
Alexa Fluor 594
NBP2-99678AF594
Alexa Fluor 647
NBP2-99678AF647
Alexa Fluor 700
NBP2-99678AF700
Alexa Fluor 750
NBP2-99678AF750
Allophycocyanin
NBP2-99678APC
Biotin
NBP2-99678B
DyLight 350
NBP2-99678UV
DyLight 405
NBP2-99678V
DyLight 488
NBP2-99678G
DyLight 550
NBP2-99678R
DyLight 594
NBP2-99678DL594
DyLight 650
NBP2-99678C
DyLight 680
NBP2-99678FR
DyLight 755
NBP2-99678IR
FITC
NBP2-99678F
HRP
NBP2-99678H
Janelia Fluor 525
NBP2-99678JF525
Janelia Fluor 549
NBP2-99678JF549
Janelia Fluor 585
NBP2-99678JF585
Janelia Fluor 635
NBP2-99678JF635
Janelia Fluor 646
NBP2-99678JF646
Janelia Fluor 669
NBP2-99678JF669
PE
NBP2-99678PE
PerCP
NBP2-99678PCP
Unconjugated
NBP2-99678-100ul
mFluor Violet 450 SE
NBP2-99678MFV450
mFluor Violet 500 SE
NBP2-99678MFV500
mFluor Violet 610 SE
NBP2-99678MFV610
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Serpin A7/TBG Antibody [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
Produced in rabbits immunized with purified, recombinant Human Serpin A7/TBG (Accession#: NP_000345.2; Met 1-Ala 415)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SERPINA7
Purity
Antigen and protein A Affinity-purified
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Applications/Dilutions

Dilutions
  • ELISA
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Antigen and protein A Affinity-purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for Serpin A7/TBG Antibody [CoraFluor™ 1]

  • antitrypsin), member 7
  • FLJ17820
  • member 7
  • Serpin A7
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)
  • T4-binding globulin
  • TBG
  • TBGclade A (alpha-1 antiproteinase
  • thyroxin-binding globulin
  • thyroxine-binding globulin

Background

Thyroxine Binding Globulin (TBG) is one of three proteins responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3 triiodothyronine (T3) in the bloodstream, along with transthyretin and albumin. TBG has the highest affinity for T4 and T3, but is present in the lowest concentration of the three proteins. Despite its low concentration, TBG carries the majority of T4 in serum. Due to the very low serum concentration of T4 & T3, TBG is rarely more than 25% saturated with ligand. Unlike transthyretin and albumin, TBG has a single binding site for T4/T3. Genomically, TBG is a serpin, although it has no inhibitory function like many other members of this class of proteins. TBG is synthesized primarily in the liver.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SERPINA7