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SDHD Antibody

Images

 
Immunohistochemistry-Paraffin: SDHD Antibody [NBP1-92372] - Staining of human liver shows moderate to strong granular cytoplasmic positivity in hepatocytes.
Immunohistochemistry-Paraffin: SDHD Antibody [NBP1-92372] - Staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.
Immunohistochemistry-Paraffin: SDHD Antibody [NBP1-92372] - Staining of human kidney shows moderate to strong granular cytoplasmic positivity in cells in tubules.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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SDHD Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: RTPVVRPAHISAFLQDRPIPEWCGVQHIHLSPSHHSGSKAASLHW
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SDHD
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20-1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
SDHD Protein (NBP1-92372PEP)
Publications
Read Publication using NBP1-92372.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for SDHD Antibody

  • CBT1
  • CII-4
  • cybS
  • PGL
  • PGL1
  • QPs3
  • SDH4
  • succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial
  • Succinate dehydrogenase complex subunit D
  • succinate dehydrogenase complex, subunit D, integral membrane protein
  • succinate dehydrogenase ubiquinone cytochrome B small subunit
  • Succinate-ubiquinone oxidoreductase cytochrome b small subunit
  • Succinate-ubiquinone reductase membrane anchor subunit

Background

SDHD is part of Complex II. Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The subunit D protein is one of two integral membrane proteins anchoring the complex to the matrix side of the membrane. Mutations in SDHD have been linked to hereditary paraganglioma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for SDHD Antibody (NBP1-92372)(1)

Reviews for SDHD Antibody (NBP1-92372) (0)

There are no reviews for SDHD Antibody (NBP1-92372). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for SDHD Antibody (NBP1-92372). (Showing 1 - 1 of 1 FAQ).

  1. I want to use SDHD antibody (NBP1-92372) to detect mouse IHC sample, can this antibody recognize mouse epitope?
    • NBP1-92372 has only been validated for use in human, hence we cannot guarantee the usage in mouse. If you are interested in trying this antibody in mouse you would qualify for our Innovators Reward Program. Through this program if you complete an online review with image, detailing your positive or negative results we will send you a discount voucher for 100% of the purchase price of the reviewed product.

Secondary Antibodies

 

Isotype Controls

Additional SDHD Products

Research Areas for SDHD Antibody (NBP1-92372)

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Blogs on SDHD.

HIF Antibodies: Beyond HIF-1 alpha
The hypoxia inducible factors are a family of heterodimeric transcription factors which are activated in response to lowered oxygen levels, or hypoxia. Although it may seem that HIF-1 alpha receives all the attention, other HIF antibodies, such as the...  Read full blog post.

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Bioinformatics

Gene Symbol SDHD
Entrez
Uniprot