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SCP1 Antibody

Images

 
Immunohistochemistry-Paraffin: SCP1 Antibody [NBP2-54674] - Staining of human testis shows high expression.
Immunohistochemistry-Paraffin: SCP1 Antibody [NBP2-54674] - Staining of human endometrium shows low expression as expected.
Orthogonal Strategies: Immunohistochemistry-Paraffin: SCP1 Antibody [NBP2-54674] - Staining in human testis and endometrium tissues using anti-SYCP1 antibody. Corresponding SYCP1 RNA-seq data are presented for ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

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SCP1 Antibody Summary

Immunogen
This antibody was developed against a Recombinant Protein corresponding to amino acids: TLGGDSTFFKSFNKCTEDDFEFPFAKTNLSKNGENIDSDPALQKVNFLPVLEQVGNSDCHYQEGLKDSDLENSEGLSRVYSKLYKEAEKIKKWKVSTEAELRQKESKLQENRKIIEAQRKAIQEL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SYCP1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
SCP1 Recombinant Protein Antigen (NBP2-54674PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for SCP1 Antibody

  • Cancer/testis antigen 8
  • CT8MGC104417
  • HOM-TES-14
  • SCP1SCP-1
  • synaptonemal complex protein 1

Background

The synaptonemal complex is a multiprotein complex that mediates synapses during the zygotene stage and then disintegrates. Resulting from chromosome pairing interactions, the synaptonemal complex unites homologous chromosomes during the prophase stage of meiosis.

Synaptonemal complex protein 1 (SCP1) is a major component of the transverse filaments of synaptonemal complex. SCP1 is therefore critical to proper homologus chromosome pairing.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Additional SCP1 Products

Array NBP2-54674

Research Areas for SCP1 Antibody (NBP2-54674)

Find related products by research area.

Blogs on SCP1.

Using SCP3/SYCP3 Antibodies as Meiosis Markers in Gametogenesis and DNA Repair Studies
The synaptonemal complex (SC) is a protein structure that forms during the synapsis of homologous chromosomes during meiosis. This structure is involved in the processes of chromosome synapsis, genetic recombination and subsequent chromosome segregati...  Read full blog post.

SCP1 a Potential Cancer Target for Immunotherapy
Synaptonemal Complex Protein 1 (SCP1) is a novel tumor antigen that belongs to the growing family of cancer/testis antigens (CTA). SCP-1 is known to be selectively expressed during the meiotic prophase of spermatocytes and is involved in the pairing o...  Read full blog post.

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Bioinformatics

Gene Symbol SYCP1