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SCN3A Antibody

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Immunohistochemistry-Paraffin: SCN3A Antibody [NBP3-14469] - Immunohistochemistry of formalin-fixed, paraffin-embedded human cerebellum after heat-induced antigen retrieval.

Product Details

Summary
Reactivity Hu, Pm, PmSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

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SCN3A Antibody Summary

Description
Product can be stored undiluted at 4C for up to 1 month.
Immunogen
Synthetic 18 amino acid peptide from internal region of human SCN3A.
Epitope
Internal
Specificity
Human SCN3A. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Primate (94%), Monkey (94%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
SCN3A
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Proteinase K antigen retrieval was used for Immunohistochemistry with formalin-fixed paraffin-embedded human tissues.

Reactivity Notes

Expected reactivity based on percent sequence identity: Orangutan, Gibbon, Marmoset, Mouse, Bovine, Guinea pig (89%), Rat, Hamster, Canine (83%)

Packaging, Storage & Formulations

Storage
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SCN3A Antibody

  • brain III voltage-gated sodium channel
  • KIAA1356
  • NAC3
  • Nav1.3
  • SCN3A
  • Sodium channel protein brain III subunit alpha
  • sodium channel protein type 3 subunit alpha
  • Sodium channel protein type III subunit alpha
  • sodium channel, voltage-gated, type III, alpha polypeptide
  • sodium channel, voltage-gated, type III, alpha subunit
  • Voltage-gated sodium channel subtype III
  • Voltage-gated sodium channel subunit alpha Nav1.3

Background

SCN3A is a member of the sodium channel alpha subunit family and mediates the voltage-dependent sodium ion permeability of excitable membranes. It assumes an opened or closed conformation in response to voltage differences across the membrane; the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional SCN3A Products

Array NBP3-14469

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Blogs on SCN3A

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Bioinformatics

Gene Symbol SCN3A