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SAH3 Antibody [Janelia Fluor® 585]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 585

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SAH3 Antibody [Janelia Fluor® 585] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residues 50 and 100 of human adenosylhomocysteinase 3 (KIAA0828) using the numbering given in entry NP_056143.1 (GeneID 23382).
Localization
Cytoplasm
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
AHCYL2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for SAH3 Antibody [Janelia Fluor® 585]

  • adenosylhomocysteinase-like 2
  • AdoHcyase 3
  • ADOHCYASE3
  • EC 3.3.1.1
  • FLJ21719
  • KIAA0828S-adenosylhomocysteine hydrolase-like 2
  • putative adenosylhomocysteinase 3
  • S-adenosylhomocysteine hydrolase-like protein 2
  • S-adenosyl-L-homocysteine hydrolase 3

Background

In mammals, S-Adenosylhomocysteine hydrolase (SAH3 / AdoHcyase) catalyzes the hydrolysis of S-adenosylhomocysteine to form adenosine and homocysteine. AdoHcy is the product of all adenosylmethionine (AdoMet)-dependent biological transmethylations. These reactions have a wide range of products, and are common in all facets of biometabolism. As a product inhibitor, elevated levels of AdoHcy suppress AdoMet-dependent transmethylations. Thus, SAH3 is a regulator of biological transmethylation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional SAH3 Products

Array NB100-401JF585

Research Areas for SAH3 Antibody (NB100-401JF585)

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Blogs on SAH3

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Bioinformatics

Gene Symbol AHCYL2