S100A4 Products

Description

S100A4 is encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Bioinformatics

Entrez	20198 Mouse 24615 Rat 6275 Human
Uniprot	AAH16300 Human NM_002961 Human NP_002952.1 Human NP_062427 Human P26447 Human
Product By Gene ID	6275
Alternate Names	18A2 Calvasculin CAPLS100 calcium binding protein A4 (calcium protein, calvasculin, metastasin fibroblast-specific protein-1,42A FSP1 leukemia multidrug resistance associated protein malignant transformation suppression 1 Metastasin MTS1 murine placental homolog) P9KA PEL98 Placental calcium-binding protein Protein Mts1 protein S100-A4 S100 calcium binding protein A4 S100 calcium-binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog) S100 calcium-binding protein A4

Research Areas for S100A4

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Cancer

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Epithelial-Mesenchymal Transition (EMT) Markers Epithelial-Mesenchymal Transition (EMT) is the trans-differentiation of stationary epithelial cells into motile mesenchymal cells. During EMT, epithelial cells lose their junctions and apical-basal polarity, reorganize their cytoskeleton, undergo a...    Read more.

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