RTKN Antibody (2E5)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: ICC/IF, WB.

Showing Publications 1 - 2 of 2.

Publications using H00006242-M01	Applications	Species
Pusapati GV, Eiseler T, Rykx A et al. Protein kinase D regulates RhoA activity via rhotekin phosphorylation. Journal of Biological Chemistry. 2012-03-16 [PMID: 22228765] (WB, Human)	WB	Human
Shankar J, Messenberg A, Chan J et al. Pseudopodial actin dynamics control epithelial-mesenchymal transition in metastatic cancer cells Cancer Res 2010-05-01 [PMID: 20388789] (ICC/IF, Human)	ICC/IF	Human

Array H00006242-M01

• RTKN Antibodies
• RTKN Lysate
• RTKN Proteins