Home » Collagen II » Collagen II Proteins » Recombinant Human Pro-Collagen II Protein, CF
Novus Biologicals products are now on bio-techne.com

Recombinant Human Pro-Collagen II Protein, CF

 (1 Publication)
 See All Related
Submit a Review

Images

 
There are currently no images for Collagen II (7589-CL).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Enzyme Activity
Format
Carrier-Free

Order Details

Novus Biologicals, part of Bio-Techne, offers 100% Guarantee

Recombinant Human Pro-Collagen II Protein, CF Summary

Details of Functionality
Measured by the cleavage of its C-terminal propeptide by Recombinant Human BMP&#x2011;1/PCP (Catalog&#160;# <a class=NoLineLink href='http://www.rndsystems.com/product_results.aspx?k=1927-ZN'>1927-ZN</a>).<br />&gt;50% of full-length Pro-Collagen II is cleaved by Recombinant Human BMP‑1/PCP (Catalog&nbsp;# <A class=NoLineLink href="http://www.rndsystems.com/product_results.aspx?k=1927-ZN">1927-ZN</A>), as measured under the described conditions. <br /><br />
Accession #
N-terminal Sequence
His & Asp1242
Protein/Peptide Type
Recombinant Enzymes
Gene
COL2A1
Endotoxin Note
<1.000 EU per 1 µg of the protein by the LAL method.

Applications/Dilutions

Dilutions
  • Enzyme Activity
Theoretical MW
78 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
SDS-PAGE
92-100 kDa, 65-70 kDa, 36 kDa, reducing conditions
Publications
Read Publication using
7589-CL in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Buffer
Supplied as a 0.2 μm filtered solution in Tris and NaCl.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Recombinant Human Pro-Collagen II Protein, CF

  • Alpha-1 type II collagen
  • ANFH
  • AOM
  • cartilage collagen
  • Chondrocalcin
  • COL11A3
  • COL2A1
  • Collagen 2
  • collagen alpha-1(II) chain
  • Collagen II
  • collagen II, alpha-1 polypeptide
  • collagen type 2
  • collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphysealdysplasia, congenital)
  • collagen, type II, alpha 1
  • Collagen-2
  • MGC131516
  • SEDC

Background

Type II collagen is an essential component of cartilage. It is essential for skeletal development and for the ability of cartilage to resist compressive forces. Type II collagen is a homotrimer of a1(II) chains. Defects in Type II collagen are the cause of numerous diseases, including chondrodysplasias and arthritis (1). This recombinant mini pro-a1(II) collagen consists of the N‑terminal propeptide, 108 Gly-X-Y repeats, and the C‑terminal propeptide. Proteolytic processing of the C‑terminal propeptide by the procollagen C-proteinase (BMP-1) releases chondrocalcin, a calcium binding protein.
  1. Kuivaniemi H. et al. (1997) Hum. Mutat. 9:300.

Customers Who Viewed This Item Also Viewed...

ACF Antibody
NBP1-90271
Western Blot ACF Antibody
Immunohistochemistry-Paraffin ACF Antibody
Immunohistochemistry-Paraffin ACF Antibody
Species: Hu
Applications: IHC, IHC-P, WB
Aggrecan
Neoepitope Antibody -
NB100-74350
Western Blot Aggrecan Neoepitope Antibody - BSA Free
Western Blot Aggrecan Neoepitope Antibody - BSA Free
Immunocytochemistry/ Immunofluorescence Aggrecan Neoepitope Antibody - BSA Free
(32 Publications)
Species: Bv, Ca, Hu, Mu, Po, Rt
Applications: Flow, ICC/IF, IHC, IHC-Fr, IHC-P, WB
SOX9 Antibody
[Unconjugated]
AF3075
Immunocytochemistry SOX9 Antibody [Unconjugated]
Western Blot SOX9 Antibody [Unconjugated]
Immunocytochemistry SOX9 Antibody [Unconjugated]
(2 Reviews)
(145 Publications)
Species: Hu
Applications: ICC, Simple Western, WB
COX-2 Antibody
NB100-689
Immunohistochemistry-Paraffin COX-2 Antibody
Simple Western COX-2 Antibody
(1 Review)
(36 Publications)
Species: Hu, Rt
Applications: IHC, IHC-Fr, IHC-P, Simple Western, WB
MMP-13 [HRP]
DM1300
N/A MMP-13 [HRP]
N/A MMP-13 [HRP]
(33 Publications)
Species: Hu
Applications: ELISA
Myelin Protein
Zero Antibody
NB100-1607
Immunohistochemistry Myelin Protein Zero Antibody
Immunocytochemistry/ Immunofluorescence Myelin Protein Zero Antibody
(16 Publications)
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IP, WB
Collagen X alpha 1
Antibody - Azide and ...
NBP3-03757
Collagen X alpha 1 Antibody - Azide and BSA Free
(2 Publications)
Species: Rt
Applications: WB
Ornithine
Decarboxylase Antibod ...
NBP2-32887
Immunohistochemistry-Paraffin Ornithine Decarboxylase Antibody (ODC1/485)
Immunocytochemistry/ Immunofluorescence Ornithine Decarboxylase Antibody (ODC1/485)
Western Blot Ornithine Decarboxylase Antibody (ODC1/485)
(1 Review)
(2 Publications)
Species: Hu, Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-P, WB
PMP22 Antibody
(Hu1) - Azide and BSA ...
NBP2-80913
Immunohistochemistry PMP22 Antibody (Hu1) - Azide and BSA Free
Species: Bv(-), Hu, Mu(-), Pm, Rt(-)
Applications: IHC, IHC-P, WB
Collagen I Antibody
NB600-408
Immunohistochemistry-Paraffin Collagen I Antibody
Immunohistochemistry-Paraffin Collagen I Antibody
Immunohistochemistry-Paraffin Collagen I Antibody
(16 Reviews)
(322 Publications)
Species: Bv, Hu, Mu, Po, Rb, Rt
Applications: ELISA, FLISA, ICC/IF, IHC, IHC-Fr, IHC-P, IP, KD, MiAr, PAGE, WB
PCNA Antibody
(PC10)
NB500-106
Immunocytochemistry/ Immunofluorescence PCNA Antibody (PC10)
Western Blot PCNA Antibody (PC10)
Flow Cytometry PCNA Antibody (PC10)
(5 Reviews)
(45 Publications)
Species: Ch, Dr, Fi, Hu, Mar, Mu, Po, Pm, Rb, Rt, Ye, Ze
Applications: ChIP, ChIP, ELISA, Flow, ICC/IF, IHC-FrFl, IHC, IHC-Fr, IHC-P, IP, Simple Western, WB
DAX1/NR0B1
Antibody (H7431)
PP-H7431-00
DAX1/NR0B1 Antibody (H7431)
(2 Publications)
Species: Hu
Applications: WB
TNF-alpha
[Unconjugated]
210-TA
SDS-PAGE TNF-alpha [Unconjugated]
Bioactivity TNF-alpha [Unconjugated]
SEC-MALS TNF-alpha [Unconjugated]
(3 Reviews)
(803 Publications)
Species: Hu
Applications: BA
beta-Catenin
Antibody [Unconjugate
AF1329
Western Blot beta-Catenin Antibody [Unconjugated]
Chromatin Immunoprecipitation (ChIP) beta-Catenin Antibody [Unconjugated]
Simple Western beta-Catenin Antibody [Unconjugated]
(2 Reviews)
(31 Publications)
Species: Hu, Mu, Rt
Applications: ChIP, CyTOF-ready, ICC, IHC, ICFlow, Simple Western, WB
iNOS Antibody -
BSA Free
NB300-605
Western Blot iNOS Antibody - BSA Free
Western Blot iNOS Antibody - BSA Free
Western Blot iNOS Antibody - BSA Free
(3 Reviews)
(130 Publications)
Species: Hu, Mu, Po, Rt
Applications: Flow, IB, ICC/IF, IHC, IHC-Fr, IHC-P, In vitro, WB
IL-6 [HRP]
M6000B
N/A IL-6 [HRP]
N/A IL-6 [HRP]
N/A IL-6 [HRP]
(635 Publications)
Species: Mu
Applications: ELISA
BMP-2
[Unconjugated]
355-BM
Bioactivity BMP-2 [Unconjugated]
(187 Publications)
Species: Hu, Mu, Rt
Applications: BA
IGF-I/IGF-1
[Unconjugated]
291-G1
SDS-PAGE IGF-I/IGF-1 [Unconjugated]
Bioactivity IGF-I/IGF-1 [Unconjugated]
Mass Spectrometry IGF-I/IGF-1 [Unconjugated]
(217 Publications)
Species: Hu
Applications: BA

Publications for Collagen II (7589-CL)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Cell Culture.


Filter By Application
Cell Culture
(1)
All Applications
Filter By Species
Human
(1)
All Species

Reviews for Collagen II (7589-CL) (0)

There are no reviews for Collagen II (7589-CL). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

FAQs for Collagen II (7589-CL) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Additional Collagen II Products

Blogs on Collagen II

There are no specific blogs for Collagen II, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Balb/3T3 mouse embryonic fibroblast cell line stained with Collagen I antibody. IHC-P image submitted by a verified customer review.
Collagen I Antibody
NB600-408-0.1mg
1 µg/lane of Recombinant Human TNF-alpha was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa.
TNF-alpha [Unconjugated]
210-TA-005

Contact Information

Product PDFs

  PDF SDS
  PDF Datasheet
  Request CofA

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Recombinant Human Pro-Collagen II Protein, CF and receive a gift card or discount.


Bioinformatics

Gene Symbol COL2A1
Uniprot