Novus Biologicals products are now on bio-techne.com

RBX1 Antibody

Images

 
Immunohistochemistry;RBX1 Antibody[NBP3-30392]Detection of human ROC1 by immunohistochemistry. Sample: FFPE section of human osteosarcoma. Antibody: Affinity purified rabbit anti-ROC1 used at a dilution of 1:1,000 . ...read more
Immunohistochemistry;RBX1 Antibody[NBP3-30395]Detection of human ROC1 by immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-ROC1 used at a dilution of 1:1,000 ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Standard Curve Range
[Standard Curve Range]
Sensitivity
[Sensitivity]

Order Details

Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

RBX1 Antibody Summary

Immunogen
between 1 and 50
Standard Curve Range
[Standard Curve Range]
Sensitivity
[Sensitivity]
Assay Type
[Assay Type]
Sample Volume
[Sample Volume]
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RBX1
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8
Preservative
0.09% Sodium Azide
Purity
Affinity purified

Alternate Names for RBX1 Antibody

  • BA554C12.1
  • EC 6.3.2.-
  • FLJ60363
  • MGC13357
  • Protein ZYP
  • RBX1
  • Regulator of cullins 1
  • Ring Box 1
  • RING box protein 1
  • RING finger protein 75
  • ring-box 1
  • ring-box 1, E3 ubiquitin protein ligase
  • RING-box protein 1
  • RNF75
  • RNF75MGC1481
  • ROC1E3 ubiquitin-protein ligase RBX1
  • ZYP Protein

Background

ROC1 is a component of the SCF (SKP1-CUL1-F-box protein) and the CBC(VHL) (CUL2-elonging BC-VHL) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. ROC1 appears to recruit the E2 ubiquitination enzyme through the RING-type zinc finger in a manner similar to CDC34, and brings it into close proximity to the substrate. The RING-type zinc finger domain is essential for ubiquitin ligase activity. ROC1 probably also stimulates CDC34 autoubiquitination and promotes the neddylation of CUL1 and probably CUL2. ROC1 has a cytoplasmic and nuclear localization and is widely expressed in most tissues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP3-16092
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
255-SC
Species: Hu
Applications: BA
NBP1-89150
Species: Hu, Rt
Applications: IHC, IHC-P, WB
H00011026-M01
Species: Hu
Applications: ELISA, WB
NBP1-31302
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, KO, WB
NBP2-20380
Species: Hu, Mu
Applications: IHC, IHC-P, WB
NBP2-21037
Species: Hu
Applications: IHC, IHC-P, WB
NBP2-31361
Species: Hu
Applications: IHC, IHC-P, WB
NBP1-81988
Species: Hu
Applications: IHC, IHC-P
H00143384-P01
Species: Hu
Applications: ELISA, AP, PA, PAGE, WB
NBP1-85594
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
UL-812
Species: Hu, Mu, Rt
Applications: EnzAct
NBP1-49873
Species: Hu, Mu
Applications: IHC, IHC-P, PEP-ELISA, WB
NBP2-45411
Species: Hu, Mu, Rt
Applications: IHC, IHC-P, WB
NBP1-59631
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P, WB
NBP1-89522
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
NB100-58788
Species: Hu, Mu
Applications: IHC, IHC-P, IP, WB
NBP2-16818
Species: Hu
Applications: ICC/IF, IHC, IHC-Fr, WB
NBP2-75465
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, IP, WB
NBP3-30395
Species: Hu, Mu
Applications: WB, IHC

Publications for RBX1 Antibody (NBP3-30395) (0)

There are no publications for RBX1 Antibody (NBP3-30395).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for RBX1 Antibody (NBP3-30395) (0)

There are no reviews for RBX1 Antibody (NBP3-30395). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for RBX1 Antibody (NBP3-30395) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional RBX1 Products

Research Areas for RBX1 Antibody (NBP3-30395)

Find related products by research area.

Blogs on RBX1

There are no specific blogs for RBX1, but you can read our latest blog posts.
mFluor Violet Conjugated Antibodies

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our RBX1 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol RBX1