Rab25 Antibody (467657) Summary
Immunogen |
E. coli-derived recombinant human RAB25 Met1-Ala195 Accession # P57735 |
Specificity |
Detects human RAB25 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human RAB5A, 10, 11A, 27A, or 27B is observed.
|
Source |
N/A |
Isotype |
IgG2b |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
RAB25 |
Purity Statement |
Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
|
Buffer |
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
Preservative |
No Preservative |
Concentration |
LYOPH |
Reconstitution Instructions |
Sterile PBS to a final concentration of 0.5 mg/mL. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Rab25 Antibody (467657)
Background
Ras-related protein RAB25, also known as CATX-8, is a 23 kDa (unglycosylated) member of the small GTPase superfamily and RAB family of proteins. Human RAB25 is 213 amino acids (aa) in length. The mature chain runs from aa 1-210 with residues 211-213 constituting a propeptide. Residues 10-174 are noted to be RAB11-like. RAB11a, RAB11b, and RAB25 are closely related RAB proteins that are differentially expressed. Human RAB25 shares 96% aa sequence identity with mouse RAB25. Functionally, RAB25 is involved in the regulation of cell survival. Researchers have shown that RAB25 promotes invasive migration of cells and increases the rates and aggressiveness of breast and ovarian cancers. It is expressed in breast and ovarian tissues.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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