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PTEN Antibody (217702) [Biotin]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC, CyTOF-ready, Flow, KO
Clone
217702
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC847U-100UG
Alexa Fluor 405
IC847V-100UG
Alexa Fluor 488
IC847G-100UG
Alexa Fluor 532
FAB847X
Alexa Fluor 594
IC847T-100UG
Alexa Fluor 647
IC847R-100UG
Alexa Fluor 700
IC847N-100UG
Alexa Fluor 750
IC847S-100UG
Allophycocyanin
FAB847A
CoraFluor 1
FAB847CL1
DyLight 350
FAB847D
DyLight 405
FAB847E
DyLight 488
FAB847K
DyLight 550
FAB847L
DyLight 594
FAB847M
DyLight 650
FAB847W
DyLight 680
FAB847Y
DyLight 755
FAB847Z
FITC
FAB847F
HRP
FAB847H
Janelia Fluor 525
FAB847JF525
Janelia Fluor 549
FAB847I
Janelia Fluor 585
FAB847JF585
Janelia Fluor 635
FAB847JF635
Janelia Fluor 646
FAB847J
Janelia Fluor 669
FAB847JF669
PE
FAB847P
PerCP
FAB847C
Unconjugated
MAB847
mFluor Violet 450 SE
FAB847MFV450
mFluor Violet 500 SE
FAB847MFV500
mFluor Violet 610 SE
FAB847MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB847
Carrier Free
MAB847
Carrier Free
MAB847-SP
Carrier Free
IC847T-100UG
Carrier Free
IC847V-100UG
Carrier Free
IC847G-100UG
Carrier Free
IC847S-100UG
Carrier Free
IC847U-100UG
Carrier Free
IC847R-100UG
Carrier Free
IC847N-100UG
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PTEN Antibody (217702) [Biotin] Summary

Immunogen
E. coli-derived recombinant human PTEN
Thr2-Val403
Accession # P60484
Specificity
Detects human and mouse PTEN.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
PTEN
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Immunohistochemistry
  • Intracellular Staining by Flow Cytometry
  • Knockout Validated
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for PTEN Antibody (217702) [Biotin]

  • BZS
  • EC 3.1.3.16,10q23del
  • EC 3.1.3.48
  • EC 3.1.3.67
  • GLM2
  • MMAC1 phosphatase and tensin homolog deleted on chromosome 10
  • MMAC1
  • MMAC1MGC11227
  • Mutated in multiple advanced cancers 1
  • phosphatase and tensin homologDEC
  • phosphatidylinositol-34,5-trisphosphate 3-phosphatase and dual-specificityprotein phosphatase PTEN
  • PTEN
  • PTEN1
  • TEP1MHAM

Background

PTEN is a protein tyrosine phosphatase that acts as a tumor suppressor, as a lipid phosphatase that dephosphorylates the D3 position of phosphatidylinositol 3,4,5-trisphosphate and as an antagonist of the PI3k/AKT signaling pathway (1-3). PTEN structural domains includes an N-terminal phosphatase domain, a lipid binding C2 domain and a 50-amino acid C-terminal tail that contains a PD biding sequence (5). Phosporylation of the tail of the protein will suppress its activity and modify its conformation to a

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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PTEN Antibody
(217702) [Biotin]
FAB847B
PTEN Antibody (217702) [Biotin]
Species: Hu, Mu
Applications: WB, IHC, CyTOF-ready, Flow, KO

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Bioinformatics

Gene Symbol PTEN