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Proprotein Convertase 9/PCSK9 Antibody (7F2)

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Immunohistochemistry: Proprotein Convertase 9/PCSK9 Antibody (7F2) [NBP3-26436] - Image of Proprotein Convertase 9/PCSK9 Antibody (7F2) diluted at 1:100 and staining in paraffin-embedded human colon cancer performed. ...read more
Western Blot: Proprotein Convertase 9/PCSK9 Antibody (7F2) [NBP3-26436] - Positive Western Blot detected in: PC-3 whole cell lysate. All lanes: Proprotein Convertase 9/PCSK9 Antibody at 1: 2000 Secondary: Goat ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IHC
Clone
7F2
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Proprotein Convertase 9/PCSK9 Antibody (7F2) Summary

Additional Information
Recombinant monoclonal antibody expressed in HEK293F cells
Immunogen
A synthesized peptide derived from Human Proprotein Convertase 9/PCSK9 [UniProt Q8NBP7]
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
PCSK9
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry 1:50-1:200
  • Western Blot 1:500-1:5000

Packaging, Storage & Formulations

Storage
Store at -20 to -70C. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.4, 150mM NaCl and 50% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Proprotein Convertase 9/PCSK9 Antibody (7F2)

  • EC 3.4.21
  • EC 3.4.21.111
  • FH3
  • FH3neural apoptosis regulated convertase 1
  • FHCL3
  • HCHOLA3
  • hypercholesterolemia, autosomal dominant 3
  • LDLCQ1
  • NARC1
  • NARC-1
  • NARC-1convertase subtilisin/kexin type 9 preproprotein
  • NARC1EC 3.4.21.-
  • Neural apoptosis-regulated convertase 1
  • PC9
  • PCSK9
  • Proprotein Convertase 9
  • proprotein convertase subtilisin/kexin type 9
  • Subtilisin/kexin-like protease PC9

Background

PCSK9 encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PCSK9