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Proprotein Convertase 1/PCSK1 Antibody (2G12)

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Sandwich ELISA: Proprotein Convertase 1/PCSK1 Antibody (2G12) [H00005122-M01] - Detection limit for recombinant GST tagged PCSK1 is 0.03 ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
2G12
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

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Proprotein Convertase 1/PCSK1 Antibody (2G12) Summary

Description
Quality control test: Antibody Reactive Against Recombinant Protein.
Immunogen
PCSK1 (NP_000430, 652 a.a. ~ 753 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. GGRRDELEEGAPSEAMLRLLQSAFSKNSPPKQSPKKSPTAKLNIPYENFYEALEKLNKPSQLKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNEEN
Specificity
PCSK1 - proprotein convertase subtilisin/kexin type 1 (2G12)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PCSK1
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Sandwich ELISA
  • Western Blot 1:500
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Proprotein Convertase 1/PCSK1 Antibody (2G12)

  • BMIQ12;NEC1;Neuroendocrine convertase 1;PC1;PC1/3;PC3;SPC3
  • NEC1
  • PCSK1
  • Proprotein Convertase 1

Background

The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a type I proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, prorenin, proenkephalin, prodynorphin, prosomatostatin and progastrin. Mutations in this gene are thought to cause obesity. This encoded protein is associated with carcinoid tumors. The use of alternate polyadenylation sites has been found for this gene. Multiple alternatively spliced transcript variants have been described for this gene but their full length nature is not known. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PCSK1
Entrez
Uniprot