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PRAME Antibody (PRAME/9188) [Allophycocyanin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
PRAME/9188
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-26932AF350
Alexa Fluor 405
NBP3-26932AF405
Alexa Fluor 488
NBP3-26932AF488
Alexa Fluor 532
NBP3-26932AF532
Alexa Fluor 594
NBP3-26932AF594
Alexa Fluor 647
NBP3-26932AF647
Alexa Fluor 700
NBP3-26932AF700
Alexa Fluor 750
NBP3-26932AF750
Biotin
NBP3-26932B
CoraFluor 1
NBP3-26932CL1
DyLight 350
NBP3-26932UV
DyLight 405
NBP3-26932V
DyLight 488
NBP3-26932G
DyLight 550
NBP3-26932R
DyLight 594
NBP3-26932DL594
DyLight 650
NBP3-26932C
DyLight 680
NBP3-26932FR
DyLight 755
NBP3-26932IR
FITC
NBP3-26932F
HRP
NBP3-26932H
Janelia Fluor 525
NBP3-26932JF525
Janelia Fluor 549
NBP3-26932JF549
Janelia Fluor 646
NBP3-26932JF646
Janelia Fluor 669
NBP3-26932JF669
PE
NBP3-26932PE
PerCP
NBP3-26932PCP
Unconjugated
NBP3-26783-100ug
mFluor Violet 450 SE
NBP3-26932MFV450
mFluor Violet 500 SE
NBP3-26932MFV500
mFluor Violet 610 SE
NBP3-26932MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP3-26783-100ug
Azide and BSA Free
NBP3-26932
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PRAME Antibody (PRAME/9188) [Allophycocyanin] Summary

Immunogen
Recombinant fragment (around aa100-250) of human PRAME protein (exact sequence is proprietary)
Localization
Nucleus, Chromosome, Cytoplasm, Golgi apparatus, Cell membrane
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PRAME
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Alternate Names for PRAME Antibody (PRAME/9188) [Allophycocyanin]

  • cancer/testis antigen 130
  • MAPEOIP4CT130
  • melanoma antigen preferentially expressed in tumors
  • OIP-4
  • Opa-interacting protein 4
  • Opa-interacting protein OIP4
  • preferentially expressed antigen in melanoma
  • Preferentially expressed antigen of melanoma

Background

PRAME encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, this gene is also expressed in acute leukemias. Recent data from Epping et.al., (Cell, Vol. 122: 835) suggest that overexpression of PRAME frequently observed in human cancers confers growth or survival advantages by antagonizing RAR signaling.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PRAME