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PPP1R3B Antibody

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Western Blot: PPP1R3B Antibody [NBP1-79917] - Host: Rabbit. Target: PPP1R3B. Positive control (+): Rat Liver (R-LI). Negative control (-): Mouse Spleen (M-SP). Antibody concentration: 1ug/ml
Western Blot: PPP1R3B Antibody [NBP1-79917] - MCF7 Cell Lysate 1ug/ml Gel Concentration 12%

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

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PPP1R3B Antibody Summary

Description
The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.
Immunogen
The immunogen for this antibody is PPP1R3B. Peptide sequence LSSKNEASGMVAPAVQEKKVKKRVSFADNQGLALTMVKVFSEFDDPLDMP. The peptide sequence for this immunogen was taken from within the described region.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PPP1R3B
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1.0 ug/ml
Theoretical MW
31 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for PPP1R3B Antibody

  • FLJ14005
  • FLJ34675
  • GL
  • Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL
  • PPP1R4PP1 subunit R4
  • protein phosphatase 1 regulatory subunit 3B
  • Protein phosphatase 1 regulatory subunit 4
  • Protein phosphatase 1 subunit GL
  • protein phosphatase 1, regulatory (inhibitor) subunit 3B

Background

PPP1R3B, the protein phosphatase-1 (PP1) catalytic subunit (PPP1CA; MIM 176875) is regulated by targeting subunits, such as PP1R3B. PP1R3B suppresses the rate at which PP1 dephosphorylates (i.e., inactivates) glycogen phosphorylase (see PYGL; MIM 232700) and enhances the rate at which it activates glycogen synthase (see GYS2; MIM 138571) (Doherty et al., 1995 [PubMed 7498521]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PPP1R3B
Uniprot