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Polycystin 2 Antibody (1G3)

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Sandwich ELISA: Polycystin 2 Antibody (1G3) [H00005311-M02] - Detection limit for recombinant GST tagged PKD2 is 1 ng/ml as a capture antibody.
Sandwich ELISA: Polycystin 2 Antibody (1G3) [H00005311-M02] - Detection limit for recombinant GST tagged PKD2 is 1 ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
1G3
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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Polycystin 2 Antibody (1G3) Summary

Description
Quality control test: Antibody Reactive Against Recombinant Protein.
Immunogen
PKD2 (NP_000288, 261 a.a. ~ 360 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. PVSKTEKTNFKTLSSMEDFWKFTEGSLLDGLYWKMQPSNQTEADNRSFIFYENLLLGVPRIRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGP
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PKD2
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Sandwich ELISA 1:100-1:2000
  • Western Blot 1:100-1:2000
Application Notes
It has been used for ELISA and WB.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Polycystin 2 Antibody (1G3)

  • APKD2
  • Autosomal dominant polycystic kidney disease type II protein
  • MGC138466
  • MGC138468
  • PC2
  • Pc-2
  • PKD4
  • polycystic kidney disease 2 (autosomal dominant)
  • Polycystic kidney disease 2 protein
  • polycystin-2
  • polycystwin
  • R48321
  • transient receptor potential cation channel, subfamily P, member 2
  • TRPP2

Background

FUNCTION: Functions as a calcium permeable cation channel. PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. SUBUNIT: Interacts with PKD1. PKD1 requires the presence of PKD2 for stable expression. Interacts with CD2AP. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in mesenchymally derived structures in the developing embryo at day 12.5. In adult, mostly expressed in kidney.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PKD2
Uniprot