Podocin/NPHS2 Peptide Summary
Specificity |
This peptide is specific for NBP2-26057 only. |
Protein/Peptide Type |
Peptide |
Gene |
NPHS2 |
Applications/Dilutions
Dilutions |
|
Application Notes |
This peptide is useful as a blocking peptide for NBP2-26057. For further blocking peptide related protocol, click here. |
Packaging, Storage & Formulations
Storage |
Store at -20 °C. |
Preservative |
No Preservative |
Reconstitution Instructions |
For Blocking studies, reconstitute pellet in 200ul distilled water to obtain a 0.5mg/ml peptide solution. |
Alternate Names for Podocin/NPHS2 Peptide
Background
This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are
guaranteed for 3 months from date of receipt.
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